Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:290119
Soleilhavoup C, et al., Nolz1 expression is required in dopaminergic axon guidance and striatal innervation. Nat Commun. 2020 Jun 19;11(1):3111
|
|
Assay type:
|
Immunohistochemistry
|
|
MGI Accession ID:
|
MGI:8270780
|
|
Gene symbol:
|
Oprm1
|
|
Gene name:
|
opioid receptor, mu 1
|
|
Antibody:
|
anti-MOR1 (#24216)
|
|
Detection system:
|
Secondary antibody coupled to Alexa Fluor
|
|
Assay notes:
|
Nolz1-/- mutant embryos, in which the coding region of Nolz1 has been replaced by beta-Galactosidase (also referred to as Nolz1<bgal/bgal>). Zfp503<tm1.1Bpb> (neo cassette removed) has been used in the annotations, but it could be Zfp503<tm1Bpb> (neo cassette still present).
|
|
|
Results
|
Specimen
S4h WT:
embryonic day 18.5
(more  )
Specimen
S4h WT:
(close  )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 18.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
S4h Nolz1-/-:
(close )
|
Genetic Background:
|
involves: 129S6/SvEvTac * C57BL/6J
|
|
Mutant Allele(s):
|
Zfp503tm1.1Bpb/Zfp503tm1.1Bpb
|
|
Age:
|
embryonic day 18.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS26: corpus striatum |
Weak |
Regionally restricted |
S4h Nolz1-/-
|
There is a strong reduction of expression in Nolz1-/- mutant striatum.
|
|
Analysis Tools
