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Gene Expression Data
Assay Details
Assay
Reference: J:366215 Rudat C, et al., PPARG contributes to urothelial integrity in the murine ureter by activating the expression of Shh and superficial cell-specific genes. Development. 2025 Apr 15;152(8)
Assay type: RNA in situ
MGI Accession ID: MGI:8268865
Gene symbol: Ivl
Gene name: involucrin
Probe: Ivl probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 5D Ivl E16.5 control: embryonic day 16.5; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS24: intermediate cell layer of ureter Strong 5D Ivl E16.5 control Strongly expressed in S cells and I cells.
TS24: superficial cell layer of ureter Strong 5D Ivl E16.5 control Strongly expressed in S cells and I cells.
Specimen 5D Ivl E16.5 cKO: embryonic day 16.5; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: ureter Weak 5D Ivl E16.5 cKO Expression levels reduced compared to control.
Specimen 5D Ivl E18.5 control: embryonic day 18.5; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS26: intermediate cell layer of ureter Strong 5D Ivl E18.5 control Strongly expressed in S cells and I cells.
TS26: superficial cell layer of ureter Strong 5D Ivl E18.5 control Strongly expressed in S cells and I cells.
Specimen 5D Ivl E18.5 cKO: embryonic day 18.5; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: ureter Weak 5D Ivl E18.5 cKO Expression levels reduced compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/06/2026
MGI 6.29 		The Jackson Laboratory