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Gene Expression Data
Assay Details
Assay
Reference: J:366215 Rudat C, et al., PPARG contributes to urothelial integrity in the murine ureter by activating the expression of Shh and superficial cell-specific genes. Development. 2025 Apr 15;152(8)
Assay type: RNA in situ
MGI Accession ID: MGI:8268864
Gene symbol: Shh
Gene name: sonic hedgehog signaling molecule
Probe: Shh probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 5D Shh E16.5 control: embryonic day 16.5; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS24: basal cell layer of ureter Present 5D Shh E16.5 control Expression in B cells and I cells.
TS24: intermediate cell layer of ureter Present 5D Shh E16.5 control Expression in B cells and I cells.

Specimen 5D Shh E16.5 cKO: embryonic day 16.5; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: ureter Absent 5D Shh E16.5 cKO Expression is lost.

Specimen 5D Shh E18.5 control: embryonic day 18.5; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS26: basal cell layer of ureter Present 5D Shh E18.5 control Expression in B cells and I cells.
TS26: intermediate cell layer of ureter Present 5D Shh E18.5 control Expression in B cells and I cells.

Specimen 5D Shh E18.5 cKO: embryonic day 18.5; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: ureter Absent 5D Shh E18.5 cKO Expression is lost.

Specimen S12 Shh E18.5 control: embryonic day 18.5; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS26: basal cell layer of ureter Present S12_Shh E18.5 control Expression in B cells and I cells.
TS26: intermediate cell layer of ureter Present S12_Shh E18.5 control Expression in B cells and I cells.

Specimen S12 Shh E18.5 cKO: embryonic day 18.5; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: ureter Absent S12_Shh E18.5 cKO Expression is lost.

Specimen S12 Shh P7 control: postnatal day 7; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS28: basal cell layer of ureter Present S12_Shh P7 control Expression in B cells and I cells.
TS28: intermediate cell layer of ureter Present S12_Shh P7 control Expression in B cells and I cells.

Specimen S12 Shh P7 cKO: postnatal day 7; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: ureter Absent S12_Shh P7 cKO Expression is lost.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/06/2026
MGI 6.29
The Jackson Laboratory