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Gene Expression Data
Assay Details
Assay
Reference: J:366215 Rudat C, et al., PPARG contributes to urothelial integrity in the murine ureter by activating the expression of Shh and superficial cell-specific genes. Development. 2025 Apr 15;152(8)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8268809
Gene symbol: Krt5
Gene name: keratin 5
Antibody: Anti-Keratin 5 (PRB-160P)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2D KRT5 control: postnatal day 40; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS28: basal cell layer of ureter Present 2D KRT5 control Expression in B cells.
Specimen 2D KRT5 cKO: postnatal day 40; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: basal cell layer of ureter Present 2D KRT5 cKO
Specimen 3C KRT5 E14.5 control: embryonic day 14.5; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS22: ureter Absent 3C KRT5 E14.5 control
Specimen 3C KRT5 E14.5cKO: embryonic day 14.5; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: ureter Absent 3C KRT5 E14.5 cKO
Specimen 3C KRT5 E16.5 control: embryonic day 16.5; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS24: basal cell layer of ureter Present 3C KRT5 E16.5 control Expression started in a few basal cells at E16.5.
Specimen 3C KRT5 E16.5 cKO: embryonic day 16.5; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: basal cell layer of ureter Present 3C KRT5 E16.5 cKO Expression not affected compared to control.
Specimen 3C KRT5 E18.5 control: embryonic day 18.5; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS26: basal cell layer of ureter Present Regionally restricted 3C KRT5 E18.5 control Expression in about half of cells at E18.5.
Specimen 3C KRT5 E18.5 cKO: embryonic day 18.5; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: basal cell layer of ureter Present Regionally restricted 3C KRT5 E18.5 cKO Expression not affected compared to control.
Specimen 3C KRT5 P7 control: postnatal day 7; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS28: basal cell layer of ureter Present Widespread 3C KRT5 P7 control Expression in all B cells at P7.
Specimen 3C KRT5 P7 cKO: postnatal day 7; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: basal cell layer of ureter Present Widespread 3C KRT5 P7 cKO Expression not affected compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/06/2026
MGI 6.29 		The Jackson Laboratory