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Gene Expression Data
Assay Details
Assay
Reference: J:366215 Rudat C, et al., PPARG contributes to urothelial integrity in the murine ureter by activating the expression of Shh and superficial cell-specific genes. Development. 2025 Apr 15;152(8)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8268804
Gene symbol: Cdh1
Gene name: cadherin 1
Antibody: anti-CDH1
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 3C CDH1 E14.5 control: embryonic day 14.5; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS22: urothelium of ureter Present 3C CDH1 E14.5 control

Specimen 3C CDH1 E14.5 cKO: embryonic day 14.5; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: urothelium of ureter Present 3C CDH1 E14.5 cKO

Specimen 3C CDH1 E16.5 control: embryonic day 16.5; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS24: urothelium of ureter Present 3C CDH1 E16.5 contro

Specimen 3C CDH1 E16.5 cKO: embryonic day 16.5; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: urothelium of ureter Present 3C CDH1 E16.5 cKO

Specimen 3C CDH1 E18.5 control: embryonic day 18.5; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS26: urothelium of ureter Present 3C CDH1 E18.5 control

Specimen 3C CDH1 E18.5 cKO: embryonic day 18.5; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: urothelium of ureter Present Regionally restricted 3C CDH1 E18.5 cKO Expression in two-layered urothelium from E18.5 onwards.

Specimen 3C CDH1 P7 control: postnatal day 7; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS28: urothelium of ureter Present 3C CDH1 P7 control

Specimen 3C CDH1 P7 cKO: postnatal day 7; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: urothelium of ureter Present Regionally restricted 3C CDH1 P7 cKO Expression in two-layered urothelium from E18.5 onwards.

Specimen S4A CDH1 P40 control: postnatal day 40; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS28: superficial cell layer of ureter Present S4A P40 control

Specimen S4A CDH1 P40 cKO: postnatal day 40; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: superficial cell layer of ureter Present S4A P40 cKO

Specimen S4A CDH1 P7 control: postnatal day 7; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS28: superficial cell layer of ureter Present S4A P7 control

Specimen S4A CDH1 P7 cKO: postnatal day 7; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: superficial cell layer of ureter Present Regionally restricted S4A P7 cKO Cells of luminal layer significantly smaller compared to control.

Specimen S4A CDH1 E18.5 control: embryonic day 18.5; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS26: superficial cell layer of ureter Present S4A E18.5 control

Specimen S4A CDH1 E18.5 cKO: embryonic day 18.5; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: superficial cell layer of ureter Present Regionally restricted S4A E18.5 cKO Cells of luminal layer significantly smaller compared to control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/06/2026
MGI 6.29
The Jackson Laboratory