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Gene Expression Data
Assay Details
Assay
Reference: J:373931 Welton JM, et al., Loss of CMTR1 leads to gastrulation failure and early embryonic lethality. Dev Biol. 2025 Dec;528:1-12
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8262936
Gene symbol: Pou5f1
Gene name: POU domain, class 5, transcription factor 1
Antibody: anti-Oct4 (AF1759)
Detection system: Secondary antibody coupled to Alexa Fluor 647
Results
Specimen 3D Control: embryonic day 6.5 (more )
Note: Littermate control; Multi-labeled: white - Pou5f1; magenta - Cdx2 (assay MGI:8262937); green - Trp53 (assay MGI:8262938); blue - DAPI.
Structure Level Pattern Image Note
TS9: embryo Present 3D Control Oct4 , 3D Control Merge Expression is present in the epiblast.
Specimen 3D KO: embryonic day 6.5; Cmtr1em1(IMPC)J/Cmtr1em1(IMPC)J (more )
Note: Multi-labeled: white - Pou5f1; magenta - Cdx2 (assay MGI:8262937); green - Trp53 (assay MGI:8262938); blue - DAPI.
Structure Level Pattern Image Note
TS9: embryo Present 3D KO Merge , 3D KO Oct4 Expression is present in the epiblast.
Specimen 4C Control: embryonic day 7.5 (more )
Note: Littermate control; Triple labeled: yellow - Pou5f1; magenta - Cdh1 (assay MGI:8262941); green - Cdh2 (assay MGI:8262943).
Structure Level Pattern Image Note
TS11: embryo Present 4C Control Oct4 , 4C Control Merge Expression is present in the epiblast.
Specimen 4C KO: embryonic day 7.5; Cmtr1em1(IMPC)J/Cmtr1em1(IMPC)J (more )
Note: Triple labeled: yellow - Pou5f1; magenta - Cdh1 (assay MGI:8262941); green - Cdh2 (assay MGI:8262943).
Structure Level Pattern Image Note
TS11: embryo Present 4C KO Oct4 , 4C KO Merge Expression is present in the epiblast.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/24/2026
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