Map2 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:54662 Ohtsuka T, et al., Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation. EMBO J. 1999 Apr 15;18(8):2196-207
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:8262426
Gene symbol:	Map2
Gene name:	microtubule-associated protein 2

Antibody:	anti-MAP2 (2a+2b+2c; clone HM-2)
Detection system:	Secondary antibody coupled to fluorescein

Results

Specimen 3E: embryonic day 10.5 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS17: telencephalon	neuron of the forebrain	Present	Regionally restricted	3E	Only expressed in a small population of cells at the pial surface.

Specimen 3F: embryonic day 10.5; Hes1^tm1Fgu/Hes1^tm1Fgu (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS17: telencephalon	neuron of the forebrain	Present		3F	Increased in number compared with the wild-type.

Specimen 3G: embryonic day 10.5; Hes5^tm1Fgu/Hes5^tm1Fgu (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS17: telencephalon	neuron of the forebrain	Present		3G	Increased in number compared with the wild-type.

Specimen 3H: embryonic day 10.5; Hes1^tm1Fgu/Hes1^tm1Fgu, Hes5^tm1Fgu/Hes5^tm1Fgu (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS17: telencephalon	neuron of the forebrain	Present		3H	Increased in number compared with the wild-type. Neurons appeared at even greater density, with smaller and severely deformed brain.

Specimen 3I: embryonic day 10.5 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS17: telencephalon	neuron of the forebrain	Present	Regionally restricted	3I	Only expressed in a small population of cells at the pial surface.

Specimen 3J: embryonic day 10.5; Hes1^tm1Fgu/Hes1^tm1Fgu (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS17: telencephalon	neuron of the forebrain	Present		3J	Positive neurons appeared at a greater density. Some cells prematurely expressed Map2 before reaching the pial surface.

Specimen 3K: embryonic day 10.5; Hes5^tm1Fgu/Hes5^tm1Fgu (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS17: telencephalon	neuron of the forebrain	Present		3K	Positive neurons appeared at a greater density. Some cells prematurely expressed Map2 before reaching the pial surface.

Specimen 3L: embryonic day 10.5; Hes1^tm1Fgu/Hes1^tm1Fgu, Hes5^tm1Fgu/Hes5^tm1Fgu (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS17: telencephalon	neuron of the forebrain	Present		3L	Positive neurons appeared at a greater density. Some cells prematurely expressed Map2 before reaching the pial surface.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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