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Gene Expression Data
Assay Details
Assay
Reference: J:339280 Almeida SM, et al., An interaction between OTULIN and SCRIB uncovers roles for linear ubiquitination in planar cell polarity. Dis Model Mech. 2023 Aug 1;16(8)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8261410
Gene symbol: Vangl2
Gene name: VANGL planar cell polarity 2
Antibody: anti-Vangl2
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 5P +/+: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 4th ventricle Present Regionally restricted 5P' , 5P Expression was enriched at the membranes of cells lining the hindbrain ventricles.
TS17: hindbrain Present 5P , 5P' Immunostaining outlined cell membranes throughout the hindbrain.
Specimen 5Q +/+: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 4th ventricle Present Regionally restricted 5Q , 5Q' Expression was enriched at the membranes of cells lining the hindbrain ventricles. Some wild type littermates sometimes showed brighter regions of VANGL2 accumulation at cell surfaces facing the ventricles.
TS17: hindbrain Present 5Q , 5Q' Immunostaining outlined cell membranes throughout the hindbrain.
Specimen 5R delta ex3/delta ex3: embryonic day 10.5; Otulintm2e.1(EUCOMM)Hmgu/Otulintm2e.1(EUCOMM)Hmgu (more )
Note: closed neural tube
Structure Level Pattern Image Note
TS17: 4th ventricle Present Regionally restricted 5R' , 5R Expression was enriched at the membranes of cells lining the hindbrain ventricles, as in wild type.
TS17: hindbrain Present 5R , 5R' Immunostaining outlined cell membranes throughout the hindbrain, as in wild type.
Specimen 5S delta ex3/delta ex3: embryonic day 10.5; Otulintm2e.1(EUCOMM)Hmgu/Otulintm2e.1(EUCOMM)Hmgu (more )
Note: closed neural tube
Structure Level Pattern Image Note
TS17: 4th ventricle Present Regionally restricted 5S , 5S' Expression was enriched at the membranes of cells lining the hindbrain ventricles, as in wild type. The brighter regions of VANGL2 accumulation at cell surfaces facing the ventricles were not as apparent in the mutant.
TS17: hindbrain Present 5S' , 5S Immunostaining outlined cell membranes throughout the hindbrain, as in wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/15/2026
MGI 6.29 		The Jackson Laboratory