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Gene Expression Data
Assay Details
Assay
Reference: J:196581 Gui T, et al., The loss of Trps1 suppresses ureteric bud branching because of the activation of TGF-beta signaling. Dev Biol. 2013 May 15;377(2):415-27
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8235423
Gene symbol: Smurf2
Gene name: SMAD specific E3 ubiquitin protein ligase 2
Antibody: anti-Smurf2
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 5E E14.5 WT: embryonic day 14.5 (more )
Note: Double labeled: red - Smurf2; green - cytokeratin.
Structure Level Pattern Image Note
TS22: collecting duct Strong Regionally restricted 5E E14.5 WT Intense expression only in ureteric bud epithelial cells.
Specimen 5E E14.5 KO: embryonic day 14.5; Trps1tm1Ymur/Trps1tm1Ymur (more )
Note: Double labeled: red - Smurf2; green - cytokeratin.
Structure Level Pattern Image Note
TS22: collecting duct Trace Regionally restricted 5E E14.5 KO Expression levels significantly reduced compared to wild type.
Specimen 5E E16.5 WT: embryonic day 16.5 (more )
Note: Double labeled: red - Smurf2; green - cytokeratin.
Structure Level Pattern Image Note
TS24: collecting duct Strong Regionally restricted 5E E16.5 WT Intense expression only in ureteric bud epithelial cells.
Specimen 5E E16.5 KO: embryonic day 16.5; Trps1tm1Ymur/Trps1tm1Ymur (more )
Note: Double labeled: red - Smurf2; green - cytokeratin.
Structure Level Pattern Image Note
TS24: collecting duct Weak Regionally restricted 5E E16.5 KO Expression levels significantly reduced compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/15/2026
MGI 6.29 		The Jackson Laboratory