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Gene Expression Data
Assay Details
Assay
Reference: J:263373 Williams MA, et al., Colorectal Cancer-Associated Genes Are Associated with Tooth Agenesis and May Have a Role in Tooth Development. Sci Rep. 2018 Feb 14;8(1):2979
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8233856
Gene symbol: Dusp10
Gene name: dual specificity phosphatase 10
Antibody: Anti-DUSP10 (ab71309)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 2A: embryonic day 12.5 (more )
Note: Bud stage of tooth development.
Structure Level Pattern Image Note
TS20: dental placode Present Regionally restricted 2B , 2A Expression was detected at a site of proliferation of the dental placode at E12.5.
TS20: oral region mesenchyme Present Regionally restricted 2A , 2B Expression was detected in underlying ectomesenchymal cells of the dental placode, as well as in the condensed ectomesenchymal cells surrounding the oral epithelial proliferation.
TS20: oral epithelium Present 2B , 2A

Specimen 2C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: dental papilla Present 2C , 2D
TS22: enamel organ Present 2C , 2D

Specimen 2E: embryonic day 16.5 (more )
Note: Bell stage.
Structure Level Pattern Image Note
TS24: dental papilla Present 2E , 2F
TS24: dental sac Present 2E , 2F
TS24: enamel organ Present 2E , 2F

Specimen 2G: embryonic day 18.5 (more )
Note: Bell stage.
Structure Level Pattern Image Note
TS26: dental papilla Present 2H , 2G Homogenous nuclear immunostaining was observed.
TS26: dental sac Present 2H , 2G Homogenous nuclear immunostaining was observed.
TS26: enamel organ Present 2H , 2G Homogenous nuclear immunostaining was observed.

Specimen 2I: postnatal day 0 (more )
Structure Cell Type Level Pattern Image Note
TS27: incisor preameloblast Present 2J , 2K , 2I
TS27: incisor odontoblast Present Regionally restricted 2J , 2I , 2K Expression was detected in the odontoblast layer subjacent to the preameloblasts.

Specimen S5A: embryonic day 18.5 (more )
Note: Bell stage.
Structure Level Pattern Image Note
TS26: dental papilla Present S5A
TS26: dental sac Present S5A
TS26: enamel organ Present S5A

Specimen S5B: postnatal day 0 (more )
Note: Late bell stage.
Structure Cell Type Level Pattern Image Note
TS27: late bell stage tooth odontoblast Present S5B
TS27: late bell stage tooth preameloblast Present S5B
TS27: predentin Present S5B

Specimen S5C: postnatal day 0 (more )
Note: Late bell stage.
Structure Cell Type Level Pattern Image Note
TS27: late bell stage tooth odontoblast Present S5C
TS27: late bell stage tooth preameloblast Present S5C
TS27: predentin Present S5C


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/06/2026
MGI 6.29
The Jackson Laboratory