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Gene Expression Data
Assay Details
Assay
Reference: J:369355 Miyazaki N, et al., Impact of gallbladder hypoplasia on hilar hepatic ducts in biliary atresia. Commun Med (Lond). 2024 Jun 11;4(1):111
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8221399
Gene symbol: Acta2
Gene name: actin alpha 2, smooth muscle, aorta
Antibody: Anti-smooth muscle alpha-Actin (clone 1A4)
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 5a SMA f/f: embryonic day 18.5; Sox17tm2Sjm/Sox17tm2Sjm (more )
Note: Double labeled: green - Acta2; magenta - DBA.
Structure Level Pattern Image Note
TS26: gallbladder Present Regionally restricted 5a SMA f/f right Expression in smooth muscle layers in presumptive gall bladder region.
TS26: blood vessel smooth muscle Present 5a SMA f/f right Expression in vascular smooth muscle.

Specimen 5a SMA f/-: embryonic day 18.5; Sox17tm1Ysk/Sox17tm2Sjm (more )
Note: Double labeled: green - Acta2; magenta - DBA.
Structure Level Pattern Image Note
TS26: gallbladder Present Regionally restricted 5a SMA f/- right Expression in smooth muscle layers in presumptive gall bladder region.
TS26: blood vessel smooth muscle Present 5a SMA f/- right Expression in vascular smooth muscle.

Specimen 5a SMA Shh-cre;f/-: embryonic day 18.5; Shhtm1(EGFP/cre)Cjt/Shh+, Sox17tm1Ysk/Sox17tm2Sjm (more )
Note: Conditional mutant. Double labeled: green - Acta2; magenta - DBA.
Structure Level Pattern Image Note
TS26: liver and biliary system Present Regionally restricted 5A SMA Shh-cre;f/- right Border between gall bladder and cystic duct walls cannot be defined.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/06/2026
MGI 6.29
The Jackson Laboratory