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Gene Expression Data
Assay Details
Assay
Reference: J:367797 Tretiakov EO, et al., Molecular Fingerprint of Endocannabinoid Signaling in the Developing Paraventricular Nucleus of the Hypothalamus as Revealed by Single-Cell RNA-Seq and In Situ Hybridization. Cells. 2025 May 27;14(11)
Assay type: RNA in situ
MGI Accession ID: MGI:8214639
Gene symbol: Cnr1
Gene name: cannabinoid receptor 1
Results
Specimen 1b,b1: postnatal adult (more )
Note: Triple labeled: red - Cnr1; blue - Slc32a1 (assay MGI:8214638); green - Trh (assay MGI:8214640).
Structure Level Pattern Image Note
TS28: paraventricular hypothalamic nucleus Present Regionally restricted 1b1 , 1b Expression at levels more pronounced than in neighboring regions. Expression dominated in Slc17a6-expressing cells.
Specimen 1b2: postnatal adult (more )
Note: Double labeled: red - Cnr1; green - Trh (assay MGI:8214640).
Structure Level Pattern Image Note
TS28: paraventricular hypothalamic nucleus Present 1b2 Expression in paraventricular nucleus at levels more pronounced than in neighboring regions.
Specimen 1c1: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: paraventricular hypothalamic nucleus Present 1c1 High amount of expression throughout anterior-posterior axis of brain, with paraventricular nucleus highlighted in hypothalamic area.
Specimen 6a: embryonic day 15.5 (more )
Note: Double labeled: green - Cnr1; red - Crh (assay MGI:8214641).
Structure Cell Type Level Pattern Image Note
TS23: paraventricular hypothalamic nucleus parvocellular neurosecretory cell Present 6a Expression localized to majority of parvocellular (small-bodied) neurosecretory neurons expressing Crh.
Specimen 6a1: embryonic day 15.5 (more )
Note: Double labeled: green - Cnr1; red - Crh (assay MGI:8214641).
Structure Cell Type Level Pattern Image Note
TS23: paraventricular hypothalamic nucleus parvocellular neurosecretory cell Present 6a1 Expression localized to majority of parvocellular (small-bodied) neurosecretory neurons expressing Crh.
Specimen 6a2,a2': embryonic day 15.5 (more )
Note: Triple labeled: blue - Cnr1; green - Crh (assay MGI:8214641); red - Daglb (assay MGI:8214642).
Structure Cell Type Level Pattern Image Note
TS23: paraventricular hypothalamic nucleus parvocellular neurosecretory cell Present 6a2' , 6a2 Expression localized to majority of parvocellular (small-bodied) neurosecretory neurons expressing Crh.
Specimen 6a3,a3': embryonic day 15.5 (more )
Note: Triple labeled: blue - Cnr1; red - Daglb (assay MGI:8214642); green - Oxt (assay MGI:8214643).
Structure Cell Type Level Pattern Image Note
TS23: paraventricular hypothalamic nucleus parvocellular neurosecretory cell Present 6a3' , 6a3 Expression localized to majority of parvocellular (small-bodied) neurosecretory neurons expressing Crh.
Specimen 6a4,a4': embryonic day 15.5 (more )
Note: Triple labeled: blue - Cnr1; red - Daglb (assay MGI:8214642); green - Trh (assay MGI:8214640).
Structure Cell Type Level Pattern Image Note
TS23: paraventricular hypothalamic nucleus parvocellular neurosecretory cell Present 6a4 , 6a4' Expression localized to majority of parvocellular (small-bodied) neurosecretory neurons expressing Crh.
Specimen 6b1,b1': postnatal day 10 (more )
Note: Triple labeled: blue - Cnr1; red - Daglb (assay MGI:8214642); green - Trh (assay MGI:8214640).
Structure Cell Type Level Pattern Image Note
TS28: paraventricular hypothalamic nucleus parvocellular neurosecretory cell Present 6b1' , 6b1 Expression maintained at P10 in Trh-expressing parvocellular neurons.
Specimen 6b2,b2': postnatal day 10 (more )
Note: Triple labeled: blue - Cnr1; red - Daglb (assay MGI:8214642); green - Oxt (assay MGI:8214643).
Structure Cell Type Level Pattern Image Note
TS28: paraventricular hypothalamic nucleus magnocellular neurosecretory cell Present 6b2' , 6b2 Expression maintained at P10 in Oxt-expressing magnocellular neurons.
Specimen 6c: postnatal day 10 (more )
Note: Triple labeled: green - Cnr1; blue - Mgll (assay MGI:8214644); red - Oxt (assay MGI:8214643).
Structure Cell Type Level Pattern Image Note
TS28: paraventricular hypothalamic nucleus magnocellular neurosecretory cell Present 6c Expression continues in Oxt-expressing magnocellular neurons.
Specimen 6c1,c1': postnatal day 10 (more )
Note: Triple labeled: blue - Cnr1; red - Mgll (assay MGI:8214644); green - Oxt (assay MGI:8214643).
Structure Cell Type Level Pattern Image Note
TS28: paraventricular hypothalamic nucleus magnocellular neurosecretory cell Present 6c1' , 6c1 Expression continues in Oxt-expressing magnocellular neurons.
Specimen 6d2,d2': postnatal day 21 (more )
Note: Triple labeled: blue - Cnr1; red - Dagla (assay MGI:8214645); green - Trh (assay MGI:8214640).
Structure Cell Type Level Pattern Image Note
TS28: paraventricular hypothalamic nucleus parvocellular neurosecretory cell Present 6d2' , 6d2 Expression continues in Trh-expressing parvocellular neurons.
Specimen 6e: postnatal day 21 (more )
Note: Double labeled: red - Cnr1; green - Crh (assay MGI:8214641).
Structure Cell Type Level Pattern Image Note
TS28: paraventricular hypothalamic nucleus parvocellular neurosecretory cell Present 6e Expression localized to majority of parvocellular (small-bodied) neurosecretory neurons expressing Crh.
Specimen 6e1,e1': postnatal day 21 (more )
Note: Double labeled: red - Cnr1; green - Crh (assay MGI:8214641).
Structure Cell Type Level Pattern Image Note
TS28: paraventricular hypothalamic nucleus parvocellular neurosecretory cell Present 6e1' , 6e1 Expression localized to majority of parvocellular (small-bodied) neurosecretory neurons expressing Crh.
Specimen 7d: postnatal adult (more )
Note: Double labeled: green - Cnr1; red - Gfap (assay MGI:8214646).
Structure Cell Type Level Pattern Image Note
TS28: paraventricular hypothalamic nucleus neuron Present 7d Expression in presumed neurons.
TS28: paraventricular hypothalamic nucleus astrocyte Absent 7d
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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08/05/2025
MGI 6.24 		The Jackson Laboratory