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Gene Expression Data
Assay Details
Assay
Reference: J:184585 Yamamoto M, et al., The transformation suppressor gene Reck is required for postaxial patterning in mouse forelimbs. Biol Open. 2012;1(5):458-466
Assay type: RNA in situ
MGI Accession ID: MGI:8213291
Gene symbol: Wnt7a
Gene name: wingless-type MMTV integration site family, member 7A
Probe: Wnt7a probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 5C11: embryonic day 11.5; Recktm1.1Noda/Reck+ (more )
Note: right forelimb
Structure Level Pattern Image Note
TS19: forelimb bud Present 5C11
Specimen 5C12: embryonic day 11.5; Recktm1.1Noda/Recktm2.2Noda (more )
Note: right forelimb
Structure Level Pattern Image Note
TS19: forelimb bud Weak 5C12 Expression was downregulated in mutant samples.
Specimen S6D1: embryonic day 11.5; Recktm1.1Noda/Reck+ (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present S6D1
Specimen S6D2: embryonic day 11.5; Recktm1.1Noda/Reck+ (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present S6D2
Specimen S6D3: embryonic day 11.5; Recktm1.1Noda/Recktm2.2Noda (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present S6D3 Weaker expression than the control.
Specimen S6D4: embryonic day 11.5; Recktm1.1Noda/Recktm2.2Noda (more )
Structure Level Pattern Image Note
TS19: forelimb bud Weak S6D4 Weaker expression than the control, particularly in their right forelimbs.
Specimen S7A1/3: embryonic day 11.5 (more )
Note: Color-concerted and overlaid: magenta - Wnt7a; green - Reck (assay MGI:8213289).
Structure Level Pattern Image Note
TS19: forelimb bud Present S7A1 , S7A3 There was considerable overlap between the areas of abundant Wnt7a signals and the Reck-positive areas in the forelimb buds in control animals, especially in their anterior region.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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07/22/2025
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