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Gene Expression Data
Assay Details
Assay
Reference: J:137963 Roumier A, et al., Prenatal activation of microglia induces delayed impairment of glutamatergic synaptic function. PLoS One. 2008;3(7):e2595
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8210987
Gene symbol: Tyrobp
Gene name: TYRO protein tyrosine kinase binding protein
Antibody: anti-DAP12
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 1B E17: embryonic day 17.0 (more )
Note: Double labeled: red - Tyrobp; green - Adgre1 (assay MGI:8210986).
Structure Cell Type Level Pattern Image Note
TS25: hippocampus microglial cell Weak 1B E17 DAP12 , 1B E17 overlay Expressed in majority of the microglial cells, albeit at low level.
Specimen 1B P0: postnatal day 0 (more )
Note: Double labeled: red - Tyrobp; green - Adgre1 (assay MGI:8210986).
Structure Cell Type Level Pattern Image Note
TS27: hippocampus microglial cell Present 1B P0 DAP12 , 1B P0 overlay Expressed in most of the microglial cells.
Specimen 1B P3: postnatal day 3 (more )
Note: Double labeled: red - Tyrobp; green - Adgre1 (assay MGI:8210986).
Structure Cell Type Level Pattern Image Note
TS27: hippocampus microglial cell Present 1B P3 overlay , 1B P3 DAP12 The fraction of expressing microglia decreased.
Specimen 1B P7: postnatal day 7 (more )
Note: Double labeled: red - Tyrobp; green - Adgre1 (assay MGI:8210986).
Structure Cell Type Level Pattern Image Note
TS28: hippocampus microglial cell Trace 1B P7 DAP12 , 1B P7 overlay Few positive microglia were detected.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory