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Gene Expression Data
Assay Details
Assay
Reference: J:306107 Niborski LL, et al., Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model. Dis Model Mech. 2021 May 1;14(5):dmm047498
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8187723
Gene symbol: Hnf1a
Gene name: HNF1 homeobox A
Antibody: anti-HNF1A
Assay notes: Embryos and postnatal kidneys up to 2 months of age were fixed with 60% ethanol/11% formaldehyde and 10% acetic acid.
Results
Specimen 3B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cortical early proximal tubule Present 3B Expression in proximal tubules.
Specimen 3B': embryonic day 16.5; Hnf1btm2.1Sce/Hnf1b+ (more )
Structure Level Pattern Image Note
TS24: cortical early proximal tubule Weak 3B' Decreased proximal tuule expression.
TS24: pancreatic acinus Present 3B' Increased acinar expression.
Specimen S3C HNF1A WT: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: renal proximal tubule Present S3C HNF1A WT Expression in proximal tubules.
Specimen S3C HNF1A Sp2/+: embryonic day 17.5; Hnf1btm2.1Sce/Hnf1b+ (more )
Structure Level Pattern Image Note
TS25: renal proximal tubule Present S3C HNF1A Sp2/+ Expression profile similar to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory