Plxnd1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:334513 Yan K, et al., TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767
Assay type:	RNA in situ
MGI Accession ID:	MGI:8187379
Gene symbol:	Plxnd1
Gene name:	plexin D1

Probe:	Plxnd1 probe
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

Specimen Control E16.5: embryonic day 16.5; Neurod2^tm1Mhsb/Neurod2⁺, Neurod6^tm1(cre)Kan/Neurod6^tm1(cre)Kan (more

)
Note: Conditional mutant.

Structure	Cell Type	Level	Pattern	Image	Note
TS24: hippocampal formation		Present	Regionally restricted	S1_Control PlxnD1 (E16.5)	Expression was detected in hippocampal subiculum.
TS24: hippocampus	hippocampal pyramidal neuron	Present	Regionally restricted	S1_Control PlxnD1 (E16.5)	Expression was detected in Cornu ammonis 1.
TS24: piriform cortex		Present		S1_Control PlxnD1 (E16.5)

Specimen DKO E16.5: embryonic day 16.5; Neurod2^tm1Mhsb/Neurod2^tm1Mhsb, Neurod6^tm1(cre)Kan/Neurod6^tm1(cre)Kan (more

)
Note: Conditional mutant.

Structure	Cell Type	Level	Pattern	Image	Note
TS24: hippocampal formation		Weak	Regionally restricted	S1_DKO PlxnD1 (E16.5)	Expression was down in hippocampal subiculum in Neurod2/6-deficient mice compared with controls.
TS24: hippocampus	hippocampal pyramidal neuron	Weak	Regionally restricted	S1_DKO PlxnD1 (E16.5)	Expression was down in Cornu ammonis 1 in Neurod2/6-deficient mice compared with controls.
TS24: piriform cortex		Weak		S1_DKO PlxnD1 (E16.5)	Expression was down in piriform cortex in Neurod2/6-deficient mice compared with controls.

Specimen Control E18.5: embryonic day 18.5; Neurod2^tm1Mhsb/Neurod2⁺, Neurod6^tm1(cre)Kan/Neurod6^tm1(cre)Kan (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS26: corpus striatum	Present		S1_Control PlxnD1 (E18.5)
TS26: piriform cortex	Present		S1_Control PlxnD1 (E18.5)

Specimen DKO E18.5: embryonic day 18.5; Neurod2^tm1Mhsb/Neurod2^tm1Mhsb, Neurod6^tm1(cre)Kan/Neurod6^tm1(cre)Kan (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS26: corpus striatum	Present		S1_DKO PlxnD1 (E18.5)
TS26: piriform cortex	Weak		S1_DKO PlxnD1 (E18.5)	Expression was down in piriform cortex in Neurod2/6-deficient mice compared with controls.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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