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Gene Expression Data
Assay Details
Assay
Reference: J:181901 Eitzinger N, et al., Ucma is not necessary for normal development of the mouse skeleton. Bone. 2012 Mar;50(3):670-80
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8175554
Gene symbol: Ucma
Gene name: upper zone of growth plate and cartilage matrix associated
Antibody: TAGL-1
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to alkaline phosphatase
Assay notes: The antibody recognizes the uncleaved form of Ucma.
Results
Specimen 8a/a': postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: epiphyseal plate resting zone Present Regionally restricted 8a , 8a' Expressed predominantly in distal areas of neonatal epiphyseal cartilage. Expressed in the matrix of resting zone cartilage. UCMA-ab2 staining (Fig 8b) appeared somewhat more diffuse that the TAGL-1 antibody staining.
Specimen 8c: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: epiphyseal plate Weak Regionally restricted 8c Expressed predominantly in distal areas of neonatal epiphyseal cartilage.
TS28: articular cartilage Weak 8c
TS28: epiphyseal plate resting zone Weak 8c
Specimen 8e/e': postnatal day 161 (more )
Structure Level Pattern Image Note
TS28: articular cartilage Absent 8e , 8e' The uncleaved Ucma isoform (TAGL-1 staining) was no longer detectable.
TS28: epiphyseal plate Absent 8e , 8e' The uncleaved Ucma isoform (TAGL-1 staining) was no longer detectable.
Specimen S3Aa: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: epiphyseal plate resting zone Present S3Aa
TS23: femur epiphysis Present S3Aa
Specimen S3Ab: embryonic day 15.5; Ucmatm1Msto/Ucmatm1Msto (more )
Structure Level Pattern Image Note
TS23: epiphyseal plate resting zone Absent S3Ab
TS23: femur epiphysis Absent S3Ab
Specimen S3Ae: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: epiphyseal plate resting zone Present S3Ae
TS27: femur epiphysis Present S3Ae
Specimen S3Af: postnatal day 1; Ucmatm1Msto/Ucmatm1Msto (more )
Structure Level Pattern Image Note
TS27: epiphyseal plate resting zone Absent S3Af
TS27: femur epiphysis Absent S3Af
Specimen S3Ai: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: epiphyseal plate resting zone Present S3Ai
TS28: femur epiphysis Present S3Ai
TS28: articular cartilage Weak S3Ai
Specimen S3Ak: postnatal day 10; Ucmatm1Msto/Ucmatm1Msto (more )
Structure Level Pattern Image Note
TS28: epiphyseal plate resting zone Absent S3Ak
TS28: femur epiphysis Absent S3Ak
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/06/2026
MGI 6.24 		The Jackson Laboratory