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Gene Expression Data
Assay Details
Assay
Reference: J:245758 Carreno G, et al., Hypothalamic sonic hedgehog is required for cell specification and proliferation of LHX3/LHX4 pituitary embryonic precursors. Development. 2017 Sep 15;144(18):3289-3302
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8174735
Gene symbol: Pitx1
Gene name: paired-like homeodomain transcription factor 1
Antibody: Anti-Pitx1
Results
Specimen 6A: embryonic day 9.5; Hesx1tm1(cre)Jpmb/Hesx1+, Shhtm2Amc/Shh+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: Rathke's pouch Present 6A
Specimen 6B: embryonic day 9.5; Hesx1tm1(cre)Jpmb/Hesx1+, Shhtm2Amc/Shhtm2.1Amc (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: Rathke's pouch Present 6B Expression is maintained in the Rathke's pouch of the mutant.
Specimen 6E: embryonic day 10.5; Hesx1tm1(cre)Jpmb/Hesx1+, Shhtm2Amc/Shh+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: Rathke's pouch Present 6E
Specimen 6F: embryonic day 10.5; Hesx1tm1(cre)Jpmb/Hesx1+, Shhtm2Amc/Shhtm2.1Amc (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: Rathke's pouch Present 6F Expression is maintained in the Rathke's pouch of the mutant.
Specimen 6I: embryonic day 11.5; Hesx1tm1(cre)Jpmb/Hesx1+, Shhtm2Amc/Shh+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: Rathke's pouch Present 6I
Specimen 6J: embryonic day 11.5; Hesx1tm1(cre)Jpmb/Hesx1+, Shhtm2Amc/Shhtm2.1Amc (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: Rathke's pouch Present 6J Expression is maintained in the Rathke's pouch of the mutant.
Specimen 10O: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: future pituitary Present 10O
Specimen S12K: embryonic day 10.5; Hesx1tm1(cre)Jpmb/Hesx1+, Ptch1tm1Hahn/Ptch1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: Rathke's pouch Present S12K
Specimen S12L: embryonic day 10.5; Hesx1tm1(cre)Jpmb/Hesx1+, Ptch1tm1Hahn/Ptch1tm1Hahn (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: Rathke's pouch Present S12L Expression in mutant is comparable to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory