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Gene Expression Data
Assay Details
Assay
Reference: J:245758 Carreno G, et al., Hypothalamic sonic hedgehog is required for cell specification and proliferation of LHX3/LHX4 pituitary embryonic precursors. Development. 2017 Sep 15;144(18):3289-3302
Assay type: RNA in situ
MGI Accession ID: MGI:8174540
Gene symbol: Nkx2-1
Gene name: NK2 homeobox 1
Results
Specimen 5I: embryonic day 10.5; Hesx1tm1(cre)Jpmb/Hesx1+, Shhtm2Amc/Shh+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: diencephalon Present Regionally restricted 5I Nkx2-1 was broadly expressed throughout the hypothalamus in control embryos.
Specimen 5J: embryonic day 10.5; Hesx1tm1(cre)Jpmb/Hesx1+, Shhtm2Amc/Shhtm2.1Amc (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: diencephalon Present Regionally restricted 5J The expression domain was shortened in Hesx1<Cre/+>;Shh<fl/-> mutants with a lack of expression in the anterior hypothalamus.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory