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Gene Expression Data
Assay Details
Assay
Reference: J:245758 Carreno G, et al., Hypothalamic sonic hedgehog is required for cell specification and proliferation of LHX3/LHX4 pituitary embryonic precursors. Development. 2017 Sep 15;144(18):3289-3302
Assay type: RNA in situ
MGI Accession ID: MGI:8174534
Gene symbol: Bmp4
Gene name: bone morphogenetic protein 4
Results
Specimen 5C: embryonic day 10.5; Hesx1tm1(cre)Jpmb/Hesx1+, Shhtm2Amc/Shh+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: diencephalon Present Regionally restricted 5C Expression is detected in the posterior hypothalamus in the control embryos, but the expression domain does not reach the anterior hypothalamic area.
TS17: oral epithelium Present 5C
Specimen 5D: embryonic day 10.5; Hesx1tm1(cre)Jpmb/Hesx1+, Shhtm2Amc/Shhtm2.1Amc (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: diencephalon Present Regionally restricted 5D Expression is anteriorised in the mutants.
TS17: Rathke's pouch Present Regionally restricted 5D Ectopic expression of Bmp4 is in the anterior region of the mutant Rathke's pouch.
Specimen 10G: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: diencephalon Present Regionally restricted 10G Expression is detected in the posterior hypothalamus in the control embryos.
Specimen S12C: embryonic day 10.5; Hesx1tm1(cre)Jpmb/Hesx1+, Ptch1tm1Hahn/Ptch1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: diencephalon Present Regionally restricted S12C Expression is detected in developing hypothalamus.
Specimen S12D: embryonic day 10.5; Hesx1tm1(cre)Jpmb/Hesx1+, Ptch1tm1Hahn/Ptch1tm1Hahn (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: diencephalon Present Regionally restricted S12D Expression in mutant developing hypothalamus is comparable to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory