About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:229484 Conte D, et al., The apical ectodermal ridge of the mouse model of ectrodactyly Dlx5;Dlx6-/- shows altered stratification and cell polarity, which are restored by exogenous Wnt5a ligand. Hum Mol Genet. 2016 Feb 15;25(4):740-54
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8174533
Gene symbol: Tjp1
Gene name: tight junction protein 1
Antibody: anti-ZO-1
Detection system: Secondary antibody
Results
Specimen 1C wild-type: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hindlimb epithelium Present 1C wild type ZO1 Expression is at the apical membrane.

Specimen 1C DKO: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hindlimb epithelium Present 1C DKO ZO1 In this mutant expression was reduced in the apical position and appeared in the basal layer.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/06/2026
MGI 6.29
The Jackson Laboratory