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Gene Expression Data
Assay Details
Assay
Reference: J:229484 Conte D, et al., The apical ectodermal ridge of the mouse model of ectrodactyly Dlx5;Dlx6-/- shows altered stratification and cell polarity, which are restored by exogenous Wnt5a ligand. Hum Mol Genet. 2016 Feb 15;25(4):740-54
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8174532
Gene symbol: Cdh1
Gene name: cadherin 1
Antibody: Anti-E-Cadherin (610181; Clone 36)
Detection system: Secondary antibody
Results
Specimen 1C wild-type: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hindlimb epithelium Present 1C wild type Ecad Expression is at the basolateral membrane.

Specimen 1C DKO: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hindlimb epithelium Present Non-Uniform 1C DKO Ecad In this mutant there is normal expression on the lateral cell borders, a reduction of the basal expression and the appearance of apical expression compared to wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/06/2026
MGI 6.29
The Jackson Laboratory