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Gene Expression Data
Assay Details
Assay
Reference: J:229484 Conte D, et al., The apical ectodermal ridge of the mouse model of ectrodactyly Dlx5;Dlx6-/- shows altered stratification and cell polarity, which are restored by exogenous Wnt5a ligand. Hum Mol Genet. 2016 Feb 15;25(4):740-54
Assay type: RNA in situ
MGI Accession ID: MGI:8174530
Gene symbol: Dlx2
Gene name: distal-less homeobox 2
Probe: Dlx2 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1A wild-type: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Present 1A wild-type

Specimen 1A DKO: embryonic day 11.5; Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi, Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Present Non-Uniform 1A DKO There is reduced expression in the central part.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/06/2026
MGI 6.29
The Jackson Laboratory