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Gene Expression Data
Assay Details
Assay
Reference: J:181272 Le TT, et al., Requirements for Jag1-Rbpj mediated Notch signaling during early mouse lens development. Dev Dyn. 2012 Mar;241(3):493-504
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8172425
Gene symbol: Pax6
Gene name: paired box 6
Antibody: anti-Pax6
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 5D: embryonic day 10.5; Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sortm1(Notch1)Dam (more )
Note: Double labeled: red - Pax6; green - TUNEL.
Structure Level Pattern Image Note
TS17: lens pit Present 5D Cell death localized at the lens pit hinges.
TS17: optic cup Present 5D

Specimen 5F: embryonic day 11.0; Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sortm1(Notch1)Dam (more )
Note: Double labeled: red - Pax6; green - TUNEL.
Structure Level Pattern Image Note
TS18: lens vesicle Present 5F Cell death disappeared.
TS18: retina Present 5F

Specimen 5H: embryonic day 11.5; Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sortm1(Notch1)Dam (more )
Note: Double labeled: red - Pax6; green - TUNEL.
Structure Level Pattern Image Note
TS19: lens vesicle Present 5H
TS19: retina Present 5H


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory