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Gene Expression Data
Assay Details
Assay
Reference: J:181272 Le TT, et al., Requirements for Jag1-Rbpj mediated Notch signaling during early mouse lens development. Dev Dyn. 2012 Mar;241(3):493-504
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8172424
Gene symbol: Parp1
Gene name: poly (ADP-ribose) polymerase family, member 1
Antibody: anti-cleaved PARP
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 5A: embryonic day 10.5; Jag1tm1Jlew/Jag1tm1Jlew (more )
Note: Summarized in Fig 5C.
Structure Level Pattern Image Note
TS17: lens vesicle Present 5A
Specimen 5B: embryonic day 10.5; Jag1tm1Jlew/Jag1tm1Jlew, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant. Summarized in Fig 5C.
Structure Level Pattern Image Note
TS17: lens vesicle Present 5B Significant increase in positive cells compared with controls.
Specimen not shown: embryonic day 10.5; Jag1tm1Jlew/Jag1+, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant. Summarized in Fig 5C.
Structure Level Pattern Image Note
TS17: lens vesicle Present Similar as in the control.
Specimen not shown: embryonic day 10.5; Rbpjtm1Hon/Rbpjtm1Hon (more )
Note: Summarized in Fig 5C.
Structure Level Pattern Image Note
TS17: lens vesicle Present
Specimen not shown: embryonic day 10.5; Rbpjtm1Hon/Rbpj+, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant. Summarized in Fig 5C.
Structure Level Pattern Image Note
TS17: lens vesicle Present Similar as in the control.
Specimen not shown: embryonic day 10.5; Rbpjtm1Hon/Rbpjtm1Hon, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant. Summarized in Fig 5C.
Structure Level Pattern Image Note
TS17: lens vesicle Present Similar as in the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory