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Gene Expression Data
Assay Details
Assay
Reference: J:181272 Le TT, et al., Requirements for Jag1-Rbpj mediated Notch signaling during early mouse lens development. Dev Dyn. 2012 Mar;241(3):493-504
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8172384
Gene symbol: Cryg
Gene name: crystallin gamma complex
Antibody: anti-gamma-crystallin
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 3D: postnatal day 0; Jag1tm1Jlew/Jag1tm1Jlew (more )
Structure Cell Type Level Pattern Image Note
TS27: lens fiber lens fiber cell Present 3D
Specimen 3E: postnatal day 0; Jag1tm1Jlew/Jag1+, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS27: lens fiber lens fiber cell Present 3E Similar as in the control.
Specimen 3F: postnatal day 0; Jag1tm1Jlew/Jag1tm1Jlew, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS27: lens fiber lens fiber cell Present 3F Positive differentiated fiber cells were seen with a smaller lens size.
Specimen not shown: embryonic day 15.5; Jag1tm1Jlew/Jag1tm1Jlew, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS23: lens fiber lens fiber cell Present Abnormal extrusion of positive lens tissue into the anterior chamber or the mesenchymal space around the persistent lens stalk was seen.
Specimen not shown: embryonic day 15.5; Rbpjtm1Hon/Rbpjtm1Hon, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS23: lens fiber lens fiber cell Present Abnormal extrusion of positive lens tissue into the anterior chamber or the mesenchymal space around the persistent lens stalk was seen.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory