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Gene Expression Data
Assay Details
Assay
Reference: J:364229 Cantu Gutierrez ME, et al., Mapping the transcriptional and epigenetic landscape of organotypic endothelial diversity in the developing and adult mouse. Nat Cardiovasc Res. 2025 Mar 17;
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8172362
Gene symbol: Cldn5
Gene name: claudin 5
Antibody: anti-Claudin-5 (4C3C2) (352588)
Detection system: Alexa Fluor 488
Assay notes: single-molecule fluorescent in situ hybridization (smFISH)
Results
Specimen 6e E12.5 CLDN5: embryonic day 12.5 (more )
Note: Double labeled: yellow - Cldn5; magenta - Mfsd2a (assay MGI:8172354).
Structure Cell Type Level Pattern Image Note
TS20: brain vascular element endothelial cell Present 6e Mfsd2a CLDN5 E12.5 , 6e Mfsd2a CLDN5 E12.5 inset
Specimen 6e P7 CLDN5: postnatal day 7 (more )
Note: Double labeled: yellow - Cldn5; magenta - Mfsd2a (assay MGI:8172354).
Structure Cell Type Level Pattern Image Note
TS28: brain vascular element endothelial cell Present 6e Mfsd2a CLDN5 P7 inset , 6e Mfsd2a CLDN5 P7
Specimen 6e Adult CLDN5: postnatal adult (more )
Note: Double labeled: yellow - Cldn5; magenta - Mfsd2a (assay MGI:8172354).
Structure Cell Type Level Pattern Image Note
TS28: brain vascular element endothelial cell Present 6e Mfsd2a CLDN5 Adult , 6e Mfsd2a CLDN5 Adult inset
Specimen 6f E12.5 CLDN5: embryonic day 12.5 (more )
Note: Double labeled: yellow - Cldn5; magenta - Abcb1a (assay MGI:8172355).
Structure Cell Type Level Pattern Image Note
TS20: brain vascular element endothelial cell Present 6f Abcb1a CLDN5 E12.5 , 6f Abcb1a CLDN5 E12.5 inset
Specimen 6f P7 CLDN5: postnatal day 7 (more )
Note: Double labeled: yellow - Cldn5; magenta - Abcb1a (assay MGI:8172355).
Structure Cell Type Level Pattern Image Note
TS28: brain vascular element endothelial cell Present 6f Abcb1a CLDN5 P7 , 6f Abcb1a CLDN5 P7 inset
Specimen 6f Adult CLDN5: postnatal adult (more )
Note: Double labeled: yellow - Cldn5; magenta - Abcb1a (assay MGI:8172355).
Structure Cell Type Level Pattern Image Note
TS28: brain vascular element endothelial cell Present 6f Abcb1a CLDN5 Adult inset , 6f Abcb1a CLDN5 Adult
Specimen 6h E12.5 CLDN5 (upper): embryonic day 12.5 (more )
Note: Double labeled: yellow - Cldn5 protein; magenta - Cldn5 mRNA (assay MGI:8172356).
Structure Cell Type Level Pattern Image Note
TS20: brain vascular element endothelial cell Present 6h Cldn5 CLDN5 E12.5 inset , 6h Cldn5 CLDN5 E12.5
Specimen 6h P7 CLDN5 (upper): postnatal day 7 (more )
Note: Double labeled: yellow - Cldn5 protein; magenta - Cldn5 mRNA (assay MGI:8172356).
Structure Cell Type Level Pattern Image Note
TS28: brain vascular element endothelial cell Present 6h Cldn5 CLDN5 P7 inset , 6h Cldn5 CLDN5 P7
Specimen 6h Adult CLDN5 (upper): postnatal adult (more )
Note: Double labeled: yellow - Cldn5 protein; magenta - Cldn5 mRNA (assay MGI:8172356).
Structure Cell Type Level Pattern Image Note
TS28: brain vascular element endothelial cell Present 6h Cldn5 CLDN5 Adult inset , 6h Cldn5 CLDN5 Adult
Specimen 6h E12.5 CLDN5 (middle: embryonic day 12.5 (more )
Note: Double labeled: yellow - Cldn5; magenta - Plagl1 (assay MGI:8172357).
Structure Cell Type Level Pattern Image Note
TS20: brain vascular element endothelial cell Present 6h Plagl1 CLDN5 E12.5 , 6h Plagl1 CLDN5 E12.5 inset
Specimen 6h P7 CLDN5 (middle: postnatal day 7 (more )
Note: Double labeled: yellow - Cldn5; magenta - Plagl1 (assay MGI:8172357).
Structure Cell Type Level Pattern Image Note
TS28: brain vascular element endothelial cell Present 6h Plagl1 CLDN5 P7 inset , 6h Plagl1 CLDN5 P7
Specimen 6h Adult CLDN5 (middle: postnatal adult (more )
Note: Double labeled: yellow - Cldn5; magenta - Plagl1 (assay MGI:8172357).
Structure Cell Type Level Pattern Image Note
TS28: brain vascular element endothelial cell Present 6h Plagl1 CLDN5 Adult , 6h Plagl1 CLDN5 Adult inset
Specimen 6h E12.5 CLDN5 (lower): embryonic day 12.5 (more )
Note: Double labeled: yellow - Cldn5; magenta - Dbp (assay MGI:8172358).
Structure Cell Type Level Pattern Image Note
TS20: brain vascular element endothelial cell Present 6h Dbp CLDN5 E12.5 inset , 6h Dbp CLDN5 E12.5
Specimen 6h P7 CLDN5 (lower): postnatal day 7 (more )
Note: Double labeled: yellow - Cldn5; magenta - Dbp (assay MGI:8172358).
Structure Cell Type Level Pattern Image Note
TS28: brain vascular element endothelial cell Present 6h Dbp CLDN5 P7 , 6h Dbp CLDN5 P7 inset
Specimen 6h Adult CLDN5 (lower): postnatal adult (more )
Note: Double labeled: yellow - Cldn5; magenta - Dbp (assay MGI:8172358).
Structure Cell Type Level Pattern Image Note
TS28: brain vascular element endothelial cell Present 6h Dbp CLDN5 Adult , 6h Dbp CLDN5 Adult inset
Specimen 7f E12.5 CLDN5 (left): embryonic day 12.5 (more )
Note: Double labeled: yellow - Cldn5; magenta - Stmn2 (assay MGI:8172359).
Structure Cell Type Level Pattern Image Note
TS20: brain vascular element endothelial cell Present 7f Stmn2 CLDN5 E12.5 , 7f Stmn2 CLDN5 E12.5 inset
Specimen 7f P7 CLDN5 (left): postnatal day 7 (more )
Note: Double labeled: yellow - Cldn5; magenta - Stmn2 (assay MGI:8172359).
Structure Cell Type Level Pattern Image Note
TS28: brain vascular element endothelial cell Present 7f Stmn2 CLDN5 P7 , 7f Stmn2 CLDN5 P7 inset
Specimen 7f Adult CLDN5 (left): postnatal adult (more )
Note: Double labeled: yellow - Cldn5; magenta - Stmn2 (assay MGI:8172359).
Structure Cell Type Level Pattern Image Note
TS28: brain vascular element endothelial cell Present 7f Stmn2 CLDN5 Adult , 7f Stmn2 CLDN5 Adult inset
Specimen 7i E12.5 CLDN5 (right): embryonic day 12.5 (more )
Note: Double labeled: yellow - Cldn5; magenta - Foxq1 (assay MGI:8172360).
Structure Cell Type Level Pattern Image Note
TS20: brain vascular element endothelial cell Present 7i Foxq1 CLDN5 E12.5 , 7i Foxq1 CLDN5 E12.5 inset
Specimen 7i P7 CLDN5 (right): postnatal day 7 (more )
Note: Double labeled: yellow - Cldn5; magenta - Foxq1 (assay MGI:8172360).
Structure Cell Type Level Pattern Image Note
TS28: brain vascular element endothelial cell Present 7i Foxq1 CLDN5 P7 , 7i Foxq1 CLDN5 P7 inset
Specimen 7i Adult CLDN5 (right): postnatal adult (more )
Note: Double labeled: yellow - Cldn5; magenta - Foxq1 (assay MGI:8172360).
Structure Cell Type Level Pattern Image Note
TS28: brain vascular element endothelial cell Present 7i Foxq1 CLDN5 Adult inset , 7i Foxq1 CLDN5 Adult
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/15/2026
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