Pomc RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:245758 Carreno G, et al., Hypothalamic sonic hedgehog is required for cell specification and proliferation of LHX3/LHX4 pituitary embryonic precursors. Development. 2017 Sep 15;144(18):3289-3302
Assay type:	RNA in situ
MGI Accession ID:	MGI:8169606
Gene symbol:	Pomc
Gene name:	pro-opiomelanocortin-alpha

Probe:

Pomc probe

Results

3L ©

Specimen 3L: embryonic day 18.5; Hesx1^tm1(cre)Jpmb/Hesx1⁺, Shh^tm2Amc/Shh⁺ (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS26: arcuate nucleus	Present		3L

3M ©

Specimen 3M: embryonic day 18.5; Hesx1^tm1(cre)Jpmb/Hesx1⁺, Shh^tm2Amc/Shh^tm2.1Amc (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS26: arcuate nucleus	Absent		3M

5K ©

Specimen 5K: embryonic day 10.5; Hesx1^tm1(cre)Jpmb/Hesx1⁺, Shh^tm2Amc/Shh⁺ (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS17: diencephalon	Present	Regionally restricted	5K	Expression is detected in the anterior hypothalamus in the control embryos.

5L ©

Specimen 5L: embryonic day 10.5; Hesx1^tm1(cre)Jpmb/Hesx1⁺, Shh^tm2Amc/Shh^tm2.1Amc (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS17: diencephalon	Ambiguous		5L	Expression is lost in the anterior hypothalamus in the mutant embryos.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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