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Gene Expression Data
Assay Details
Assay
Reference: J:245758 Carreno G, et al., Hypothalamic sonic hedgehog is required for cell specification and proliferation of LHX3/LHX4 pituitary embryonic precursors. Development. 2017 Sep 15;144(18):3289-3302
Assay type: RNA in situ
MGI Accession ID: MGI:8169552
Gene symbol: Ptch1
Gene name: patched 1
Probe: Ptch1 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1S: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: diencephalon Present Regionally restricted 1S Expression was detected in the anterior hypothalamus and the posterior hypothalamus.
TS15: Rathke's pouch Present Regionally restricted 1S Expression was detected in the rostral region of the evaginating Rathke's pouch.
Specimen 1T: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: diencephalon Present Regionally restricted 1T Expression was detected in the anterior hypothalamus and the posterior hypothalamus.
TS17: Rathke's pouch Present Regionally restricted 1T Expression was detected at the boundary of Rathke's pouch with the oral ectoderm and pharyngeal endoderm.
Specimen 1U: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: diencephalon Present Regionally restricted 1U Expression was detected in the anterior hypothalamus.
TS19: Rathke's pouch Present Regionally restricted 1U Expression was detected in the ventral region of the pinched-off pouch.
Specimen 1V: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hypothalamus Present Regionally restricted 1V Expression was detected in the anterior hypothalamus.
TS20: remnant of Rathke's pouch Present Regionally restricted 1V Ptch1 transcripts are localised within the periluminal epithelium.
TS20: adenohypophysis Present Regionally restricted 1V Ptch1 transcripts are localised in the marginal zone.
Specimen 1W: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: remnant of Rathke's pouch Present Regionally restricted 1W Ptch1 transcripts are localised within the periluminal epithelium.
TS22: adenohypophysis Present Regionally restricted 1W Ptch1 transcripts are localised in the marginal zone.
Specimen 1X: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: diencephalon Present Regionally restricted 1X Expression was detected around the 3rd ventricle.
TS26: remnant of Rathke's pouch Present Regionally restricted 1X Ptch1 transcripts are localised within the periluminal epithelium.
TS26: adenohypophysis Present Regionally restricted 1X Ptch1 transcripts are localised in the marginal zone.
Specimen 4K: embryonic day 10.5; Hesx1tm1(cre)Jpmb/Hesx1+, Shhtm2Amc/Shh+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: diencephalon Present Regionally restricted 4K Expression is detected in the anterior hypothalamus in the control embryos.
TS17: Rathke's pouch Present 4K
Specimen 4L: embryonic day 10.5; Hesx1tm1(cre)Jpmb/Hesx1+, Shhtm2Amc/Shhtm2.1Amc (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: diencephalon Ambiguous 4L Expression is lost in the anterior hypothalamus in the mutant embryos.
TS17: Rathke's pouch Absent 4L
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/06/2026
MGI 6.24 		The Jackson Laboratory