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Gene Expression Data
Assay Details
Assay
Reference: J:245758 Carreno G, et al., Hypothalamic sonic hedgehog is required for cell specification and proliferation of LHX3/LHX4 pituitary embryonic precursors. Development. 2017 Sep 15;144(18):3289-3302
Assay type: RNA in situ
MGI Accession ID: MGI:8169414
Gene symbol: Gli1
Gene name: GLI-Kruppel family member GLI1
Probe: Gli1 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1M: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: Rathke's pouch Present 1M
Specimen 1N: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: Rathke's pouch Present 1N
Specimen 1O: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: Rathke's pouch Present 1O
Specimen 1P: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: remnant of Rathke's pouch Present Regionally restricted 1P Expression was detected in the periluminal epithelium.
Specimen 1Q: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: remnant of Rathke's pouch Present Regionally restricted 1Q Expression was detected in the periluminal epithelium.
Specimen 1R: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: adenohypophysis Present Regionally restricted 1R Expression was in the marginal zone of the anterior pituitary.
Specimen 4I: embryonic day 10.5; Hesx1tm1(cre)Jpmb/Hesx1+, Shhtm2Amc/Shh+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: Rathke's pouch Strong 4I
Specimen 4J: embryonic day 10.5; Hesx1tm1(cre)Jpmb/Hesx1+, Shhtm2Amc/Shhtm2.1Amc (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: Rathke's pouch Trace Regionally restricted 4J Expression was barely detectable and mostly restricted to the posterior region in the mutant Rathke's pouch.
TS17: head mesenchyme Present Regionally restricted 4J Expression was detected in head mesenchyme underlying the anterior hypothalamus in the mutant.
Specimen 8I: embryonic day 10.5; Hesx1tm1(cre)Jpmb/Hesx1+, Ptch1tm1Hahn/Ptch1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: Rathke's pouch Present 8I
Specimen 8J: embryonic day 10.5; Hesx1tm1(cre)Jpmb/Hesx1+, Ptch1tm1Hahn/Ptch1tm1Hahn (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: Rathke's pouch Present 8J
Specimen 8K: embryonic day 12.5; Hesx1tm1(cre)Jpmb/Hesx1+, Ptch1tm1Hahn/Ptch1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: remnant of Rathke's pouch Present 8K
Specimen 8L: embryonic day 12.5; Hesx1tm1(cre)Jpmb/Hesx1+, Ptch1tm1Hahn/Ptch1tm1Hahn (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: remnant of Rathke's pouch Present 8L
Specimen 8M: embryonic day 14.5; Hesx1tm1(cre)Jpmb/Hesx1+, Ptch1tm1Hahn/Ptch1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: adenohypophysis Present 8M
Specimen 8N: embryonic day 14.5; Hesx1tm1(cre)Jpmb/Hesx1+, Ptch1tm1Hahn/Ptch1tm1Hahn (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: adenohypophysis Present Regionally restricted 8N A remarkable increase in Gli1 expression is observed throughout the anterior pituitary in the mutants relative to the control embryos, including the marginal zone.
Specimen 8O: embryonic day 18.5; Hesx1tm1(cre)Jpmb/Hesx1+, Ptch1tm1Hahn/Ptch1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: adenohypophysis Present 8O' , 8O
Specimen 8P: embryonic day 18.5; Hesx1tm1(cre)Jpmb/Hesx1+, Ptch1tm1Hahn/Ptch1tm1Hahn (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: adenohypophysis Present Regionally restricted 8P' , 8P A remarkable increase in Gli1 expression is observed throughout the anterior pituitary in the mutants relative to the control embryos, including the marginal zone.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory