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Gene Expression Data
Assay Details
Assay
Reference: J:178173 Mastracci TL, et al., Nkx2.2 and Arx genetically interact to regulate pancreatic endocrine cell development and endocrine hormone expression. Dev Biol. 2011 Nov 1;359(1):1-11
Assay type: RT-PCR
MGI Accession ID: MGI:8161716
Gene symbol: Ins1
Gene name: insulin I
Probe: Mm01950294_s1
Assay notes: Quantitative RT-PCR. Relative expression was normalized to Ppib.
Results
Image: S4I Ins1 ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex Note
WT P0 TS27: pancreas Present Not Specified Not Specified Not Specified
Arx deltaendo P0 TS27: pancreas Present (a) Not Specified involves: 129/Sv * Black Swiss Arxtm1Gldn/?, Tg(Neurog3-cre)C1Able/0Not Specified Conditional mutant. Arx<tm1Gldn>/Arx<tm1Gldn> in female, Arx<tm1Gldn>/Y in male.
Nkx2.2 null P0 TS27: pancreas Absent Not Specified involves: 129X1/SvJ * Black Swiss Nkx2-2tm1Jlr/Nkx2-2tm1JlrNot Specified
Nkx2.2 null;Arx deltaendo P0 TS27: pancreas Absent Not Specified involves: 129/Sv * 129X1/SvJ * Black Swiss Arxtm1Gldn/?, Nkx2-2tm1Jlr/Nkx2-2tm1Jlr, Tg(Neurog3-cre)C1Able/0Not Specified Conditional mutant. Arx<tm1Gldn>/Arx<tm1Gldn> in female, Arx<tm1Gldn>/Y in male.
Notes:
(a) Trend for increased expression (p=0.07).

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory