Gcg RT-PCR Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:178173 Mastracci TL, et al., Nkx2.2 and Arx genetically interact to regulate pancreatic endocrine cell development and endocrine hormone expression. Dev Biol. 2011 Nov 1;359(1):1-11
Assay type:	RT-PCR
MGI Accession ID:	MGI:8161705
Gene symbol:	Gcg
Gene name:	glucagon

Probe:	Mm00801712_m1
Assay notes:	Quantitative RT-PCR. Relative expression was normalized to Ppib.

Results

	Sample Information		Bands	Other Sample Information
Lane	Age	Structure	Size Not Specified	Amount	Genetic Background	Mutant Allele(s)	Sex	Note
WT	P0	TS27: pancreas	Present	Not Specified	Not Specified		Not Specified
Arx deltaendo	P0	TS27: pancreas	Weak (a)	Not Specified	involves: 129/Sv * Black Swiss	Arx^tm1Gldn/?, Tg(Neurog3-cre)C1Able/0	Not Specified	Conditional mutant.
Nkx2.2 null	P0	TS27: pancreas	Present (b)	Not Specified	involves: 129X1/SvJ * Black Swiss	Nkx2-2^tm1Jlr/Nkx2-2^tm1Jlr	Not Specified
Nkx2.2 null;Arx deltaendo	P0	TS27: pancreas	Trace (c)	Not Specified	involves: 129/Sv * 129X1/SvJ * Black Swiss	Arx^tm1Gldn/?, Nkx2-2^tm1Jlr/Nkx2-2^tm1Jlr, Tg(Neurog3-cre)C1Able/0	Not Specified	Conditional mutant.

Notes:
(a) Reduced expression compared with the wild-type.
(b) Reduced expression compared with the wild-type, but higher than that of Arx deltaendo and Nkx2.2 null;Arx deltaendo.
(c) Expression was further reduced compared with the Arx deltaendo.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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