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Gene Expression Data
Assay Details
Assay
Reference: J:275030 Ferder IC, et al., Meiotic gatekeeper STRA8 suppresses autophagy by repressing Nr1d1 expression during spermatogenesis in mice. PLoS Genet. 2019 May;15(5):e1008084
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8161501
Gene symbol: Sycp3
Gene name: synaptonemal complex protein 3
Antibody: anti-SCP-3 (D-1, sc-74569)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 9B Stra8-/- SYCP3: postnatal day 10; Stra8tm1Dcp/Stra8tm1Dcp (more )
Note: Double labeled: green - Sycp3; red - H2ax (assay MGI:8161505).
Structure Level Pattern Image Note
TS28: germ cell of testis Present Regionally restricted 9B Stra8-/-;Nr1d1+/+ SYCP3 , 9B Stra8-/-;Nr1d1+/+ Nuclear distribution of expression was absent.
Specimen 9B Stra8-/-;Nr1d1-/- SYCP3: postnatal day 10; Nr1d1tm1Ven/Nr1d1tm1Ven, Stra8tm1Dcp/Stra8tm1Dcp (more )
Note: Double labeled: green - Sycp3; red - H2ax (assay MGI:8161505).
Structure Level Pattern Image Note
TS28: germ cell of testis Present Regionally restricted 9B Stra8-/-;Nr1d1-/- , 9B Stra8-/-;Nr1d1-/- SYCP3 Nuclear expression was present.
Specimen S9C Nr1d1+/+ SYCP3: postnatal day 10; Stra8tm1Dcp/Stra8tm1Dcp (more )
Note: Double labeled: green - Sycp3; red - H2ax (assay MGI:8161505).
Structure Level Pattern Image Note
TS28: germ cell of testis Present S9C Nr1d1+/+ , S9C Nr1d1+/+ SYCP3
Specimen S9C Nr1d1-/- SYCP3: postnatal day 10; Nr1d1tm1Ven/Nr1d1tm1Ven, Stra8tm1Dcp/Stra8tm1Dcp (more )
Note: Double labeled: green - Sycp3; red - H2ax (assay MGI:8161505).
Structure Level Pattern Image Note
TS28: germ cell of testis Present S9C Nr1d1-/- SYCP3 , S9C Nr1d1-/- Authors report no appreciable effect on meiotic initiation.
Specimen S10B Wild-type SYCP3: postnatal (more )
Note: Double labeled: green - Sycp3; red - Sycp1 (assay MGI:8161506).
Structure Level Pattern Image Note
TS28: germ cell of testis Present S10B Wild-type , S10B Wild-type SYCP3
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/15/2026
MGI 6.29 		The Jackson Laboratory