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Gene Expression Data
Assay Details
Assay
Reference: J:310316 Li H, et al., Expression and function of NUMB in odontogenesis. Biomed Res Int. 2013;2013:182965
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8158356
Gene symbol: Numb
Gene name: NUMB endocytic adaptor protein
Antibody: anti-NUMB (ab14140)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen E13.5 not shown: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: tooth Absent No expression in tooth germ.
Specimen S1: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: tooth Absent S1_left , S1_right No expression in tooth germ.
Specimen E18.5 not shown: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: tooth Absent No expression in tooth germ.
Specimen 4B: postnatal day 3 (more )
Structure Cell Type Level Pattern Image Note
TS27: cervical loop preameloblast Present 4B Expression in ameloblast progenitors in cervical loop.
TS27: incisor enamel organ ameloblast Strong Regionally restricted 4B Strong expression in ameloblasts on labial surfac.
TS27: incisor dental papilla odontoblast Strong Regionally restricted 4B Strong expression in odontoblasts at both labial and lingual surfaces.
TS27: incisor dental pulp dental pulp cell Present Regionally restricted 4B Expression in dental pulp cells in close vicinity to the odontoblasts.
Specimen 4C: postnatal day 3 (more )
Structure Cell Type Level Pattern Image Note
TS27: molar enamel organ ameloblast Strong 4C , 4C1
TS27: molar dental papilla odontoblast Strong 4C1 , 4C
TS27: molar dental pulp dental pulp cell Present Regionally restricted 4C1 , 4C Expression in dental pulp cells in close vicinity to the odontoblasts
Specimen 4D: postnatal day 3 (more )
Structure Cell Type Level Pattern Image Note
TS27: incisor enamel organ ameloblast Strong 4D1 , 4D
TS27: molar dental papilla odontoblast Strong 4D , 4D1
TS27: molar dental pulp dental pulp cell Present Regionally restricted 4D , 4D1 Expression in dental pulp cells in close vicinity to the odontoblasts
Specimen 5A: postnatal day 5 (more )
Structure Cell Type Level Pattern Image Note
TS28: enamel organ ameloblast Present 5A2 , 5A1 , 5A
TS28: dental papilla odontoblast Present 5A2 , 5A1 , 5A Expression in immature odontoblasts.
TS28: dental pulp dental pulp cell Absent 5A1 , 5A , 5A2 No expression in dental pulp cells.
Specimen 5B: postnatal day 5 (more )
Structure Cell Type Level Pattern Image Note
TS28: enamel organ ameloblast Present 5B1 , 5B2 , 5B
TS28: dental papilla odontoblast Present 5B , 5B1 , 5B2
TS28: dental pulp dental pulp cell Absent 5B1 , 5B , 5B2 No expression in dental pulp cells.
Specimen 6A: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: stratum intermedium Present 6A Expression more specifically limited to cells of stratum intermedium.
Specimen 6A1: postnatal day 7 (more )
Structure Cell Type Level Pattern Image Note
TS28: enamel organ ameloblast Present 6A1 Expression more defined in immature ameloblasts.
TS28: dental papilla odontoblast Trace 6A1 Very low expression levels in immature odontoblasts.
Specimen 6B: postnatal day 7 (more )
Structure Cell Type Level Pattern Image Note
TS28: enamel organ ameloblast Present 6B2 , 6B , 6B1 Expression more defined in immature ameloblasts.
TS28: dental papilla odontoblast Trace 6B1 , 6B2 , 6B Very low expression levels in immature odontoblasts.
Specimen S2 Numb: postnatal day 5 (more )
Structure Cell Type Level Pattern Image Note
TS28: incisor ameloblast Present S2_Numb right , S2_Numb left
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/06/2026
MGI 6.29 		The Jackson Laboratory