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Gene Expression Data
Assay Details
Assay
Reference: J:337458 Waldhauser V, et al., PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development. Cells. 2023 Jun 6;12(12)
Assay type: RNA in situ
MGI Accession ID: MGI:7865687
Gene symbol: Plp1
Gene name: proteolipid protein (myelin) 1
Probe: Plp1 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 6D E16.5 Ctrl: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: spinal cord Absent 6D Ctrl E16.5
Specimen 6D E16.5 deltaSox10: embryonic day 16.5; Pbrm1tm1Zhwa/Pbrm1tm1Zhwa, Tg(Sox10-cre)1Wdr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: spinal cord Absent 6D deltaSox10 E16.5
Specimen 6D P0 Ctrl: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: spinal cord Weak 6D Ctrl P0
Specimen 6D P0 deltaSox10: postnatal day 0; Pbrm1tm1Zhwa/Pbrm1tm1Zhwa, Tg(Sox10-cre)1Wdr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: spinal cord Trace 6D deltaSox10 P0 Substantially fewer expressing cells compared to control.
Specimen 6D P7 Ctrl: postnatal day 7 (more )
Structure Level Pattern Image Note
TS27: corpus callosum Present 6D Ctrl P7
Specimen 6D P7 deltaSox10: postnatal day 7; Pbrm1tm1Zhwa/Pbrm1tm1Zhwa, Tg(Sox10-cre)1Wdr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: spinal cord Weak 6D deltaSox10 P7 Number of expressing cells significantly lower than control.
Specimen 6D P14 Ctrl: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: spinal cord Present 6D Ctrl P14
Specimen 6D P14 deltaSox10: postnatal day 14; Pbrm1tm1Zhwa/Pbrm1tm1Zhwa, Tg(Sox10-cre)1Wdr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: spinal cord Weak 6D deltaSox10 P14 Number of expressing cells significantly lower than control.
Specimen 6D P21 Ctrl: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: spinal cord Present 6D Ctrl P21
Specimen 6D P21 deltaSox10: postnatal day 21; Pbrm1tm1Zhwa/Pbrm1tm1Zhwa, Tg(Sox10-cre)1Wdr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: spinal cord Weak 6D deltaSox10 P21 Difference in number of expressing cells (26-31%) roughly matched overall difference in number of oligodendrocytes.
Specimen P7 Ctrl not shown: postnatal day 7 (more )
Note: Data shown in Figure 8F.
Structure Level Pattern Image Note
TS28: corpus callosum Present
Specimen P7 deltaSox10 not shown: postnatal day 7; Pbrm1tm1Zhwa/Pbrm1tm1Zhwa, Tg(Sox10-cre)1Wdr/0 (more )
Note: Conditional mutant. Data shown in Figure 8F.
Structure Level Pattern Image Note
TS28: corpus callosum Weak Number of expressing cells significantly lower than control.
Specimen P21 Ctrl not shown: postnatal day 21 (more )
Note: Data shown in Figure 8F.
Structure Level Pattern Image Note
TS28: corpus callosum Present
Specimen P21 deltaSox10 not shown: postnatal day 21; Pbrm1tm1Zhwa/Pbrm1tm1Zhwa, Tg(Sox10-cre)1Wdr/0 (more )
Note: Conditional mutant. Data shown in Figure 8F.
Structure Level Pattern Image Note
TS28: corpus callosum Weak Number of expressing cells significantly lower than control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/06/2026
MGI 6.29 		The Jackson Laboratory