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Gene Expression Data
Assay Details
Assay
Reference: J:337458 Waldhauser V, et al., PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development. Cells. 2023 Jun 6;12(12)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7865680
Gene symbol: Myrf
Gene name: myelin regulatory factor
Antibody: anti-Myrf
Results
Specimen 1D Myrf: postnatal day 0 (more )
Note: Double labeled: green - Myrf; red - Pbrm1 (assay MGI:7865665).
Structure Cell Type Level Pattern Image Note
TS27: spinal cord spinal cord oligodendrocyte Present 1D Myrf Expression in myelinating oligodendroglial cells.
Specimen 5F E16.5 Ctrl: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: spinal cord Ambiguous 5F Ctrl E16.5
Specimen 5F E16.5 deltaSox10: embryonic day 16.5; Pbrm1tm1Zhwa/Pbrm1tm1Zhwa, Tg(Sox10-cre)1Wdr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: spinal cord Ambiguous 5F deltaSox10 E16.5 Authors report no substantial reduction in number of expressing cells at E16.5.
Specimen 5F P0 Ctrl: postnatal day 0 (more )
Structure Cell Type Level Pattern Image Note
TS27: spinal cord spinal cord oligodendrocyte Present 5F Ctrl P0 Expression in myelinating oligodendroglial cells.
Specimen 5F P0 deltaSox10: postnatal day 0; Pbrm1tm1Zhwa/Pbrm1tm1Zhwa, Tg(Sox10-cre)1Wdr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: spinal cord Weak 5F deltaSox10 P0 Substantial (71%) reduction in number of expressing cells.
Specimen 5F P7 Ctrl: postnatal day 7 (more )
Structure Cell Type Level Pattern Image Note
TS28: spinal cord spinal cord oligodendrocyte Present 5F Ctrl P7 Expression in myelinating oligodendroglial cells.
Specimen 5F P7 deltaSox10: postnatal day 7; Pbrm1tm1Zhwa/Pbrm1tm1Zhwa, Tg(Sox10-cre)1Wdr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: spinal cord Weak 5F deltaSox10 P7 Substantial (55%) reduction in number of expressing cells.
Specimen 5F P14 Ctrl: postnatal day 14 (more )
Structure Cell Type Level Pattern Image Note
TS28: spinal cord spinal cord oligodendrocyte Present 5F Ctrl P14 Expression in myelinating oligodendroglial cells.
Specimen 5F P14 deltaSox10: postnatal day 14; Pbrm1tm1Zhwa/Pbrm1tm1Zhwa, Tg(Sox10-cre)1Wdr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: spinal cord Weak 5F deltaSox10 P14 Number of expressing cells significantly lower than control.
Specimen 5F P21 Ctrl: postnatal day 21 (more )
Structure Cell Type Level Pattern Image Note
TS28: spinal cord spinal cord oligodendrocyte Present 5F Ctrl P21 Expression in myelinating oligodendroglial cells.
Specimen 5F P21 deltaSox10: postnatal day 21; Pbrm1tm1Zhwa/Pbrm1tm1Zhwa, Tg(Sox10-cre)1Wdr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: spinal cord Weak 5F deltaSox10 P21 Number of expressing cells significantly lower than control.
Specimen P7 Ctrl not shown: postnatal day 7 (more )
Note: Data shown in Figure 8E.
Structure Cell Type Level Pattern Image Note
TS28: corpus callosum oligodendrocyte Present Expression in myelinating oligodendroglial cells
Specimen P7 deltaSox10 not shown: postnatal day 7; Pbrm1tm1Zhwa/Pbrm1tm1Zhwa, Tg(Sox10-cre)1Wdr/0 (more )
Note: Conditional mutant. Data shown in Figure 8E.
Structure Level Pattern Image Note
TS28: corpus callosum Weak Number of expressing cells significantly lower than control.
Specimen P21 Ctrl not shown: postnatal day 21 (more )
Note: Data shown in Figure 8E.
Structure Cell Type Level Pattern Image Note
TS28: corpus callosum oligodendrocyte Present Expression in myelinating oligodendroglial cells
Specimen P21 deltaSox10 not shown: postnatal day 21; Pbrm1tm1Zhwa/Pbrm1tm1Zhwa, Tg(Sox10-cre)1Wdr/0 (more )
Note: Conditional mutant. Data shown in Figure 8E.
Structure Level Pattern Image Note
TS28: corpus callosum Weak Number of expressing cells significantly lower than control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/06/2026
MGI 6.29 		The Jackson Laboratory