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Gene Expression Data
Assay Details
Assay
Reference: J:337458 Waldhauser V, et al., PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development. Cells. 2023 Jun 6;12(12)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7865672
Gene symbol: Sox6
Gene name: SRY (sex determining region Y)-box 6
Antibody: anti-Sox6
Results
Specimen 5B E16.5 Ctrl: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: spinal cord oligodendrocyte precursor cell Present 5B Ctrl E16.5 Expression in oligodendrocyte progenitor cells and in early pre-myelinating cells.
TS24: spinal cord spinal cord oligodendrocyte Present 5B Ctrl E16.5 Expression in oligodendrocyte progenitor cells and in early pre-myelinating cells.
Specimen 5B E16.5 deltaSox10: embryonic day 16.5; Pbrm1tm1Zhwa/Pbrm1tm1Zhwa, Tg(Sox10-cre)1Wdr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: spinal cord Present 5B deltaSox10 E16.5 Number of expressing cells comparable to control.
Specimen 5B P0 Ctrl: postnatal day 0 (more )
Structure Cell Type Level Pattern Image Note
TS27: spinal cord oligodendrocyte precursor cell Present 5B Ctrl P0 Expression in oligodendrocyte progenitor cells and in early pre-myelinating cells.
TS27: spinal cord spinal cord oligodendrocyte Present 5B Ctrl P0 Expression in oligodendrocyte progenitor cells and in early pre-myelinating cells.
Specimen 5B P0 deltaSox10: postnatal day 0; Pbrm1tm1Zhwa/Pbrm1tm1Zhwa, Tg(Sox10-cre)1Wdr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: spinal cord Weak 5B deltaSox10 P0 Number of expressing cells ~25% lower than control.
Specimen 5B P7 Ctrl: postnatal day 7 (more )
Structure Cell Type Level Pattern Image Note
TS28: spinal cord oligodendrocyte precursor cell Present 5B Ctrl P7 Expression in oligodendrocyte progenitor cells and in early pre-myelinating cells.
TS28: spinal cord spinal cord oligodendrocyte Present 5B Ctrl P7 Expression in oligodendrocyte progenitor cells and in early pre-myelinating cells.
Specimen 5B P7 deltaSox10: postnatal day 7; Pbrm1tm1Zhwa/Pbrm1tm1Zhwa, Tg(Sox10-cre)1Wdr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: spinal cord Present 5B deltaSox10 P7 Number of expressing cells not signficantly lower than control.
Specimen 5B P14 Ctrl: postnatal day 14 (more )
Structure Cell Type Level Pattern Image Note
TS28: spinal cord oligodendrocyte precursor cell Present 5B Ctrl P14 Expression in oligodendrocyte progenitor cells and in early pre-myelinating cells.
TS28: spinal cord spinal cord oligodendrocyte Present 5B Ctrl P14 Expression in oligodendrocyte progenitor cells and in early pre-myelinating cells.
Specimen 5B P14 deltaSox10: postnatal day 14; Pbrm1tm1Zhwa/Pbrm1tm1Zhwa, Tg(Sox10-cre)1Wdr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: spinal cord Present 5B deltaSox10 P14 Number of expressing cells not signficantly lower than control.
Specimen 5B P21 Ctrl: postnatal day 21 (more )
Structure Cell Type Level Pattern Image Note
TS28: spinal cord oligodendrocyte precursor cell Present 5B Ctrl P21 Expression in oligodendrocyte progenitor cells and in early pre-myelinating cells.
TS28: spinal cord spinal cord oligodendrocyte Present 5B Ctrl P21 Expression in oligodendrocyte progenitor cells and in early pre-myelinating cells.
Specimen 5B P21 deltaSox10: postnatal day 21; Pbrm1tm1Zhwa/Pbrm1tm1Zhwa, Tg(Sox10-cre)1Wdr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: spinal cord Present 5B deltaSox10 P21 Number of expressing cells not signficantly lower than control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/06/2026
MGI 6.29 		The Jackson Laboratory