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Gene Expression Data
Assay Details
Assay
Reference: J:52397 Koebbe MJ, et al., Effects of prenatal cocaine exposure on embryonic expression of sonic hedgehog. Teratology. 1999 Jan;59(1):12-9
Assay type: RNA in situ
MGI Accession ID: MGI:7858884
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: midbrain Present 1B Expression in mesencephalon.
TS17: neural tube floor plate Present Regionally restricted 1B Expression in floor plate region along entire ventral spinal cord.
TS17: notochord Present 1B Expression in longitudinal streak along notochord.
TS17: limb bud Present Regionally restricted 1B Expression distal portions of limb buds in zone of polarizing activity.
TS17: embryo endoderm Present 1B Expression in endodermal structures.
TS17: cardiovascular system Present 1B
Specimen 2A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: central nervous system Present Regionally restricted 2A Expression restricted to longitudinal region of ventral central nervous system.
Specimen 2C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: central nervous system Present Regionally restricted 2C Expression restricted to longitudinal region of ventral central nervous system.
Specimen 3A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future spinal cord Present Regionally restricted 3A Expression restricted to ventral portion of spinal cord and hindgut.
TS15: hindgut Present Regionally restricted 3A Expression restricted to ventral portion of spinal cord and hindgut.
Specimen 3C: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future midbrain Present Regionally restricted 3C Expression in ventral portion of both rostral and caudal regions.
Specimen 3E: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future spinal cord Present Regionally restricted 3E Expression in ventral portion .
TS15: notochord Present Regionally restricted 3E
Specimen 4A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forebrain Present Regionally restricted 4A Expression in ventral portion .
Specimen 4C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: midbrain Present Regionally restricted 4C Expression in ventral portion of both rostral and caudal regions.
Specimen 4E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 4E Expression in ventral portion .
TS17: notochord Present 4E
Specimen 6A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: limb bud Present Regionally restricted 6A Expression restricted to posterior region.
Specimen 6C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: limb bud Present Regionally restricted 6C Expresson limited to small region.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
MGI 6.24 		The Jackson Laboratory