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Gene Expression Data
Assay Details
Assay
Reference: J:175543 Yin Y, et al., Mesothelial- and epithelial-derived FGF9 have distinct functions in the regulation of lung development. Development. 2011 Aug;138(15):3169-77
Assay type: RNA in situ
MGI Accession ID: MGI:7855069
Gene symbol: Lef1
Gene name: lymphoid enhancer binding factor 1
Probe: GN8 cDNA
Probe preparation: Antisense RNA
Results
Specimen 3D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lung Present 3D

Specimen 3D': embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lung mesenchyme Present 3D' Expressed in both the sub-mesothelial and sub-epithelial domains.
TS20: lung epithelium Absent 3D'

Specimen 3E: embryonic day 12.5; Fgf9tm1.1Fwan/Fgf9tm1.1Fwan, Twist2tm1(cre)Dor/Twist2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: lung Present 3E Reduced expression compared with the control.

Specimen 3E': embryonic day 12.5; Fgf9tm1.1Fwan/Fgf9tm1.1Fwan, Twist2tm1(cre)Dor/Twist2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: lung mesenchyme Present Regionally restricted 3E' Reduced expression in the sub-mesothelial domain, compared with the control. Expression in the sub-epithelial domain retained.
TS20: lung epithelium Absent 3E'

Specimen 3F: embryonic day 12.5; Fgf9tm1.1Fwan/Fgf9tm1.1Fwan, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: lung Present 3F Reduced expression compared with the control.

Specimen 3F': embryonic day 12.5; Fgf9tm1.1Fwan/Fgf9tm1.1Fwan, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: lung mesenchyme Present Regionally restricted 3F' Reduced expression in the sub-epithelial domain, compared with the control. Expression in the sub-mesothelial domain retained.
TS20: lung epithelium Absent 3F'


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory