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Gene Expression Data
Assay Details
Assay
Reference: J:175387 Wu X, et al., Differentiation of the ductal epithelium and smooth muscle in the prostate gland are regulated by the Notch/PTEN-dependent mechanism. Dev Biol. 2011 Aug 15;356(2):337-49
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7852885
Gene symbol: Notch1
Gene name: notch 1
Antibody: anti-cleaved Notch1 (Val1744) antibody (anti-NICD) (#2421)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to other - see notes
Assay notes: The antibody used recognizes the cleaved form of the protein.
Results
Specimen 3A: embryonic day 17.5 (more )
Note: Tyramide signal amplification kit was used.
Structure Level Pattern Image Note
TS25: epithelium of urogenital sinus Present 3A
TS25: prostate bud Present 3A
TS25: mesenchyme of urogenital sinus Present Single cells 3A Expressed in a few cells.

Specimen 3N: embryonic day 18.5 (more )
Note: Tyramide signal amplification kit was used.
Structure Level Pattern Image Note
TS26: epithelium of urogenital sinus Present 3N
TS26: prostate bud Present 3N
TS26: mesenchyme of urogenital sinus Present Single cells 3N Expressed in a few cells.

Specimen 4B: postnatal day 14 (more )
Note: Tyramide signal amplification kit was used.
Structure Level Pattern Image Note
TS28: ventral prostatic epithelium Present 4B Expressed in the ductal epithelium and prostate buds.
TS28: smooth muscle of ventral prostate Present 4B


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory