Ldlr Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:174826 Rousselet E, et al., PCSK9 reduces the protein levels of the LDL receptor in mouse brain during development and after ischemic stroke. J Lipid Res. 2011 Jul;52(7):1383-91
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7850837
Gene symbol:	Ldlr
Gene name:	low density lipoprotein receptor

Antibody:	Anti-LDLR
Detection system:	Secondary antibody coupled to Alexa Fluor 488

Results

1B WT ©

Specimen 1B WT: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: telencephalon	Present		1B WT

1B -/- ©

Specimen 1B -/-: embryonic day 12.5; Pcsk9^tm1.2Prat/Pcsk9^tm1.2Prat (more

)

Structure	Level	Pattern	Image	Note
TS20: telencephalon	Present		1B -/-	Higher expression compared with the wild-type.

2B WT ©

Specimen 2B WT: postnatal day 7 (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebellum external granule cell layer	Present		2B WT

2B -/- ©

Specimen 2B -/-: postnatal day 7; Pcsk9^tm1.2Prat/Pcsk9^tm1.2Prat (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebellum external granule cell layer	Present		2B -/-	Higher expression compared with the wild-type.

Specimen not shown: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: main olfactory bulb	Absent			Under detection level.
TS28: olfactory tract	Absent			Under detection level.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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