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Gene Expression Data
Assay Details
Assay
Reference: J:261678 Aoidi R, et al., Mek1(Y130C) mice recapitulate aspects of human cardio-facio-cutaneous syndrome. Dis Model Mech. 2018 Mar 13;11(3):dmm031278
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7840124
Gene symbol: Mapk3
Gene name: mitogen-activated protein kinase 3
Antibody: anti-phospho-ERK1/2
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 5D +/+: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: pulmonary artery Present 5D +/+ No variation of expression between different genotypes.
Specimen 5D +/-: embryonic day 13.5; Map2k1tm1.1Chrn/Map2k1+ (more )
Structure Level Pattern Image Note
TS21: pulmonary artery Present 5D +/- No variation of expression between different genotypes.
Specimen 5D Y130C/+: embryonic day 13.5; Map2k1tm2.1Chrn/Map2k1+ (more )
Structure Level Pattern Image Note
TS21: pulmonary artery Present 5D Y130C/+ No variation of expression between different genotypes.
Specimen 5D Y130C/-: embryonic day 13.5; Map2k1tm2.1Chrn/Map2k1tm1.1Chrn (more )
Structure Level Pattern Image Note
TS21: pulmonary artery Present 5D Y130C/- No variation of expression between different genotypes.
Specimen 5D Y130C/Y130C: embryonic day 13.5; Map2k1tm2.1Chrn/Map2k1tm2.1Chrn (more )
Structure Level Pattern Image Note
TS21: pulmonary artery Present 5D Y130C/Y130C No variation of expression between different genotypes.
Specimen S4A,D: postnatal week 6 (more )
Structure Level Pattern Image Note
TS28: CA1 pyramidal cell layer Present S4D , S4A
Specimen S4B,E: postnatal week 6; Map2k1tm2.1Chrn/Map2k1tm1.1Chrn (more )
Structure Level Pattern Image Note
TS28: CA1 pyramidal cell layer Present S4E , S4B
Specimen S4C,F: postnatal week 6; Map2k1tm2.1Chrn/Map2k1tm2.1Chrn (more )
Structure Level Pattern Image Note
TS28: CA1 pyramidal cell layer Present Regionally restricted S4F , S4C Increased density of expressing cells compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory