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Gene Expression Data
Assay Details
Assay
Reference: J:352610 Ikeda S, et al., Harderian Gland Development and Degeneration in the Fgf10-Deficient Heterozygous Mouse. J Dev Biol. 2024 Jun 3;12(2)
Assay type: RNA in situ
MGI Accession ID: MGI:7798832
Gene symbol: Fgf10
Gene name: fibroblast growth factor 10
Probe: Fgf10 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3A/S8B: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: perioptic mesenchyme Present Regionally restricted 3A , S8B Relatively intense expression in an oval or crescent domain, located nasolaterally. Not expressed by developing hemangioblasts.
TS23: nasal mesenchyme Present Regionally restricted 3A Lower levels in the mesenchyme near the extraocular muscles.
TS23: nasal septum mesenchyme Present 3A Relatively intense expression.
TS23: optic nerve Present 3A lower levels
TS23: nasal gland mesenchyme Present 3A Relatively intense expression in the surrounding mesenchyme of the nasal glands.

Specimen 3G: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: eye mesenchyme Present Regionally restricted 3G Expressed in the mesenchyme abutting the emerging superficial gland.

Specimen 4A: embryonic day 19.0 (more )
Structure Level Pattern Image Note
TS26: eye mesenchyme Present Regionally restricted 4A Expressed in the sheath-like Harderian mesenchyme.
TS26: eyelid mesenchyme Present Regionally restricted 4A Expressed in a deep mesenchymal layer of the developing eyelid.

Specimen 4I/S9A: embryonic day 19.0; Fgf10tm1Ska/Fgf10+ (more )
Structure Level Pattern Image Note
TS26: perioptic mesenchyme Present Regionally restricted S9A , 4 Cont._I Expressed in the Harderian mesenchyme, where the Harderian gland primordia were missing.

Specimen S8A: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: perioptic mesenchyme Present Regionally restricted S8A Relatively intense expression in an oval or crescent domain, located nasolaterally. Not expressed by developing hemangioblasts.

Specimen S8E/E': embryonic day 19.0 (more )
Structure Level Pattern Image Note
TS26: eye mesenchyme Present Regionally restricted S8E' , S8E Expressed in the Harderian mesenchyme, not in the melanoblast or melanocyte.

Specimen S8G: embryonic day 19.0 (more )
Structure Level Pattern Image Note
TS26: perioptic mesenchyme Present Regionally restricted S8G Expressed in an oval or crescent domain. Not expressed in the mesenchyme near the elongating and cavitating Harderian glands in tubulogenesis.

Specimen S11C: embryonic day 19.0 (more )
Structure Level Pattern Image Note
TS26: eye mesenchyme Present Regionally restricted S11C Expressed in the sheath-like Harderian mesenchyme.

Specimen S12A/G: embryonic day 19.0; Fgf10tm1Ska/Fgf10+ (more )
Structure Level Pattern Image Note
TS26: eye mesenchyme Present Regionally restricted S12G , S12A Expressed in the Harderian gland mesenchyme without glandular epithelia. Round cells populated in the mesenchyme.

Specimen S12E: embryonic day 19.0; Fgf10tm1Ska/Fgf10+ (more )
Note: more caudal section of S12A
Structure Level Pattern Image Note
TS26: eye mesenchyme Present Regionally restricted S12E Expressed in the Harderian gland mesenchyme without glandular epithelia.

Specimen S12H: embryonic day 19.0; Fgf10tm1Ska/Fgf10+ (more )
Note: more rostral section of S12A
Structure Level Pattern Image Note
TS26: eye mesenchyme Present Regionally restricted S12H Expressed in the Harderian gland mesenchyme with thin tubular cells populated.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory