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Gene Expression Data
Assay Details
Assay
Reference: J:305429 Kaiser M, et al., Regulation of otocyst patterning by Tbx2 and Tbx3 is required for inner ear morphogenesis in the mouse. Development. 2021 Apr 15;148(8):dev195651
Assay type: RNA in situ
MGI Accession ID: MGI:7790971
Gene symbol: Id3
Gene name: inhibitor of DNA binding 3
Probe: Id3 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen S9 anterior control: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: otocyst Present Regionally restricted S9_anterior control Id3 Expression was detected in the posterior-ventral and dorsal regions.
Specimen S9 anterior Tbx2/3cDKO: embryonic day 10.5; Tbx2tm2.1Vmc/Tbx2tm2.1Vmc, Tbx3tm1Pa/Tbx3tm1Pa, Tg(Pax2-cre)10Shwl/0, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: otocyst Weak Regionally restricted S9_anterior Tbx2/3cDKO Id3 Expression was lost from the posterior-ventral and downregulated in the dorsal region.
Specimen S9 mid-transverse control: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: otocyst Present Regionally restricted S9_mid-transverse control Id3 Expression was detected in the posterior-ventral and dorsal regions.
Specimen S9 mid-transverse Tbx2/3cDKO: embryonic day 10.5; Tbx2tm2.1Vmc/Tbx2tm2.1Vmc, Tbx3tm1Pa/Tbx3tm1Pa, Tg(Pax2-cre)10Shwl/0, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: otocyst Weak Regionally restricted S9_mid-transverse Tbx2/3cDKO Id3 Expression was lost from the posterior-ventral and downregulated in the dorsal region.
Specimen S9 posterior control: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: otocyst Present Regionally restricted S9_posterior control Id3 Expression was detected in the posterior-ventral and dorsal regions.
Specimen S9 posterior Tbx2/3cDKO: embryonic day 10.5; Tbx2tm2.1Vmc/Tbx2tm2.1Vmc, Tbx3tm1Pa/Tbx3tm1Pa, Tg(Pax2-cre)10Shwl/0, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: otocyst Weak Regionally restricted S9_posterior Tbx2/3cDKO Id3 Expression was lost from the posterior-ventral and downregulated in the dorsal region.
Specimen S10B anterior control: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: otocyst Ambiguous S10B anterior control Id3
Specimen S10B anterior Tbx2/3cDKO: embryonic day 9.5; Tbx2tm2.1Vmc/Tbx2tm2.1Vmc, Tbx3tm1Pa/Tbx3tm1Pa, Tg(Pax2-cre)10Shwl/0, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: otocyst Ambiguous S10B anterior Tbx2/3cDKO Id3
Specimen S10B mid-transverse control: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: otocyst Ambiguous S10B mid-transverse control Id3
Specimen S10B mid-transverse Tbx2/3cDKO: embryonic day 9.5; Tbx2tm2.1Vmc/Tbx2tm2.1Vmc, Tbx3tm1Pa/Tbx3tm1Pa, Tg(Pax2-cre)10Shwl/0, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: otocyst Ambiguous S10B mid-transverse Tbx2/3cDKO Id3
Specimen S10B posterior control: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: otocyst Ambiguous S10B posterior control Id3
Specimen S10B posterior Tbx2/3cDKO: embryonic day 9.5; Tbx2tm2.1Vmc/Tbx2tm2.1Vmc, Tbx3tm1Pa/Tbx3tm1Pa, Tg(Pax2-cre)10Shwl/0, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: otocyst Ambiguous S10B posterior Tbx2/3cDKO Id3
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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