About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:305429 Kaiser M, et al., Regulation of otocyst patterning by Tbx2 and Tbx3 is required for inner ear morphogenesis in the mouse. Development. 2021 Apr 15;148(8):dev195651
Assay type: RNA in situ
MGI Accession ID: MGI:7789036
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Probe: Sox2 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen S4A anterior control: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: otocyst Present Regionally restricted S4A anterior control Sox2 Sox2 is a proneurosensory marker with expression in the ventral region along the anterior-posterior axis at E9.5.
Specimen S4A anterior Tbx2/3cDKO: embryonic day 9.5; Tbx2tm2.1Vmc/Tbx2tm2.1Vmc, Tbx3tm1Pa/Tbx3tm1Pa, Tg(Pax2-cre)10Shwl/0, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: otocyst Present Regionally restricted S4A anterior Tbx2/3cDKO Sox2 Expression in the ventral region of the otocyst was unaffected in the Tbx2/3cDKO.
Specimen S4A mid-transverse control: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: otocyst Present Regionally restricted S4A mid-transverse control Sox2 Sox2 is a proneurosensory marker with expression in the ventral region along the anterior-posterior axis at E9.5.
Specimen S4A mid-transverse Tbx2/3cDKO: embryonic day 9.5; Tbx2tm2.1Vmc/Tbx2tm2.1Vmc, Tbx3tm1Pa/Tbx3tm1Pa, Tg(Pax2-cre)10Shwl/0, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: otocyst Present Regionally restricted S4A mid-transverse Tbx2/3cDKO Sox2 Expression in the ventral region of the otocyst was unaffected in the Tbx2/3cDKO.
Specimen S4A posterior control: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: otocyst Present Regionally restricted S4A posterior control Sox2 Sox2 is a proneurosensory marker with expression in the ventral region along the anterior-posterior axis at E9.5.
Specimen S4A posterior Tbx2/3cDKO: embryonic day 9.5; Tbx2tm2.1Vmc/Tbx2tm2.1Vmc, Tbx3tm1Pa/Tbx3tm1Pa, Tg(Pax2-cre)10Shwl/0, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: otocyst Present Regionally restricted S4A posterior Tbx2/3cDKO Sox2 Expression in the ventral region of the otocyst was unaffected in the Tbx2/3cDKO.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory