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Gene Expression Data
Assay Details
Assay
Reference: J:174095 Cai Z, et al., Loss of shp2-mediated mitogen-activated protein kinase signaling in muller glial cells results in retinal degeneration. Mol Cell Biol. 2011 Jul;31(14):2973-83
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7788468
Gene symbol: Gfap
Gene name: glial fibrillary acidic protein
Results
Specimen 2I WT: postnatal day 21 (more )
Structure Cell Type Level Pattern Image Note
TS28: retina layer retinal astrocyte Present Regionally restricted 2I WT Expressed in the inner retina.
Specimen 2I cKO: postnatal day 21; Ptpn11tm1Gsf/Ptpn11tm1Gsf, Tg(Six3-cre)69Frty/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: retina layer retinal astrocyte Present 2I cKO Increased expression, with reactive Muller cell gliosis, in the mutant.
Specimen S3O: postnatal day 7 (more )
Structure Cell Type Level Pattern Image Note
TS28: retina layer retinal astrocyte Present Regionally restricted S3O Expressed in the inner retina.
Specimen S3P: postnatal day 7; Ptpn11tm1Gsf/Ptpn11tm1Gsf, Tg(Six3-cre)69Frty/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: retina layer retinal astrocyte Present Regionally restricted S3P Expressed in the inner retina, similar as in the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
MGI 6.24 		The Jackson Laboratory