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Gene Expression Data
Assay Details
Assay
Reference: J:358601 Nishino T, et al., Single Cell Multimodal Analyses Reveal Epigenomic and Transcriptomic Basis for Birth Defects in Maternal Diabetes. Nat Cardiovasc Res. 2023 Dec;2(12):1190-1203
Assay type: RNA in situ
MGI Accession ID: MGI:7788372
Gene symbol: Alx3
Gene name: aristaless-like homeobox 3
Probe: Mm-Alx3 (1127551)
Probe preparation: Antisense DNA
Visualized with: Fluorescence
Results
Specimen 3e1 Alx3: embryonic day 10.5; Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze/Gt(ROSA)26Sor+, Tg(Mef2c-cre)2Blk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: heart Present Regionally restricted 3e1 Merged , 3e1 inset i , 3e1 Alx3 Expression in subset of anterior heart field (AHF) cells.
Specimen 3e2 Alx3: embryonic day 10.5; Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze/Gt(ROSA)26Sor+, Tg(Mef2c-cre)2Blk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: heart Present Regionally restricted 3e2 Merged , 3e2 inset ii , 3e2 Alx3 Expression in subset of anterior heart field (AHF) cells.
Specimen 3f Alx3: embryonic day 10.5; Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze/Gt(ROSA)26Sor+, Tg(Mef2c-cre)2Blk/0 (more )
Note: Conditional mutant. Double labeled: red - Alx3; green - Armh4 (assay MGI:7788373).
Structure Level Pattern Image Note
TS17: outflow tract Present Regionally restricted 3f Alx3 , 3f Merged Expression in anterior heart field (AHF) at distal outflow tract region, not overlapping with Armh4 expression.
Specimen S6B dorsal Alx3: embryonic day 10.5; Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze/Gt(ROSA)26Sor+, Tg(Mef2c-cre)2Blk/0 (more )
Note: Conditional mutant. Imaged using light sheet microscopy. Double labeled: red - Alx3; green - Armh4 (assay MGI:7788373).
Structure Level Pattern Image Note
TS17: heart Present Regionally restricted ED6B dorsal Expression in cells posterior to Armh4-expressing AHF1 cells, abutting AHF1 cells of distal outflow tract.
Specimen S6B oblique Alx3: embryonic day 10.5; Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze/Gt(ROSA)26Sor+, Tg(Mef2c-cre)2Blk/0 (more )
Note: Conditional mutant. Imaged using light sheet microscopy. Double labeled: red - Alx3; green - Armh4 (assay MGI:7788373).
Structure Level Pattern Image Note
TS17: heart Present Regionally restricted ED6B oblique Expression in cells posterior to Armh4-expressing AHF1 cells, abutting AHF1 cells of distal outflow tract.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory