Cyp11a1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:173838 Manuylov NL, et al., Conditional ablation of Gata4 and Fog2 genes in mice reveals their distinct roles in mammalian sexual differentiation. Dev Biol. 2011 May 15;353(2):229-41
Assay type:	RNA in situ
MGI Accession ID:	MGI:7783657
Gene symbol:	Cyp11a1
Gene name:	cytochrome P450, family 11, subfamily a, polypeptide 1

Probe:	Cyp11a1 probe
Probe preparation:	Antisense RNA

Results

3I Control ©

Specimen 3I control: embryonic day 14.5 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS22: Leydig cell	Leydig cell	Present		3I Control

3I cKO ©

Specimen 3I GATA4cKO: embryonic day 14.5; Gata4^tm1.1Wtp/Gata4^tm1.1Wtp, Tg(Nr5a1-cre)2Klp/0 (more

)
Note: Conditional mutant.

Structure	Cell Type	Level	Pattern	Image	Note
TS22: Leydig cell	Leydig cell	Present		3I cKO	Similar as in the control, although gonad thickness was slightly reduced in the mutant.

9H control ©

Specimen 9H control: embryonic day 14.5 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS22: Leydig cell	Leydig cell	Present		9H control

9H cKO ©

Specimen 9H FOG2cKO: embryonic day 14.5; Tg(Nr5a1-cre)2Klp/0, Zfpm2^tm2Sho/Zfpm2^tm2Sho (more

)
Note: Conditional mutant. hermaphrodite

Structure	Cell Type	Level	Pattern	Image	Note
TS22: Leydig cell	Leydig cell	Present		9H cKO	Grossly normal expression.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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