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Gene Expression Data
Assay Details
Assay
Reference: J:67359 Bruneau BG, et al., Cardiomyopathy in Irx4-deficient mice is preceded by abnormal ventricular gene expression. Mol Cell Biol. 2001 Mar;21(5):1730-6
Assay type: RNA in situ
MGI Accession ID: MGI:7781771
Gene symbol: Irx2
Gene name: Iroquois homeobox 2
Probe: Irx2 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4F +/+: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: heart Present Regionally restricted 4F +/+ Expression in subset of cells near interventricular groove.
TS17: primitive ventricle Present 4F +/+ Expression in pattern overlapping that of Irx1.

Specimen 4F -/-: embryonic day 10.5; Irx4tm1Jse/Irx4tm1Jse (more )
Structure Level Pattern Image Note
TS17: primitive ventricle Strong 4F -/- Expression increased compared to control.

Specimen 4G +/+: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: heart Present Regionally restricted 4G +/+ Expression in subset of cells near interventricular groove.
TS17: primitive ventricle Present 4G +/+ Expression in pattern overlapping that of Irx1.

Specimen 4G -/-: embryonic day 10.5; Irx4tm1Jse/Irx4tm1Jse (more )
Structure Level Pattern Image Note
TS17: primitive ventricle Strong 4G -/- Expression increased compared to wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory