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Gene Expression Data
Assay Details
Assay
Reference: J:308914 Panoutsopoulos AA, et al., Pak1ip1 Loss-of-Function Leads to Cell Cycle Arrest, Loss of Neural Crest Cells, and Craniofacial Abnormalities. Front Cell Dev Biol. 2020;8:510063
Assay type: RNA in situ
MGI Accession ID: MGI:7780173
Gene symbol: Twist1
Gene name: twist basic helix-loop-helix transcription factor 1
Probe: Twist1 probe
Probe preparation: Antisense RNA
Results
Specimen 2A: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: facial prominence mesenchyme Strong 2A
TS16: fronto-nasal process mesenchyme Strong 2A
TS16: future hindbrain Present Regionally restricted 2A Expressed in the region in proximity to branchial arches 1 and 2.
TS16: 1st branchial arch mesenchyme derived from neural crest Strong 2A
TS16: 2nd branchial arch mesenchyme derived from neural crest Strong 2A
TS16: trunk mesenchyme derived from neural crest Strong 2A
Specimen 2D: embryonic day 10.0; Pak1ip1mray/Pak1ip1mray (more )
Structure Level Pattern Image Note
TS16: facial prominence mesenchyme Present 2D Overtly reduced expression levels in the facial prominences.
TS16: fronto-nasal process mesenchyme Present 2D Reduced expression compared with the wild-type.
TS16: future hindbrain Weak Regionally restricted 2D Diminished expression in the hindbrain in proximity to branchial arches 1 and 2.
TS16: 1st branchial arch mesenchyme derived from neural crest Strong 2D
TS16: 2nd branchial arch mesenchyme derived from neural crest Strong 2D
TS16: trunk mesenchyme derived from neural crest Strong 2D
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory